Abstract
Morinda citrifolia, also known as noni, is commonly used in popular medicine in Brazil. Many parts of the noni tree are utilized in such practices, including the roots, leaves and seeds. Through a search of online databases, the present article reviews 92 research studies on the biological actions of M. citrifolia. The paper will discuss the therapeutic effects of noni and its compounds in a variety of forms of presentation, focusing on studies that support its traditional use. A large and diverse number of properties were identified, which were divided into immunostimulatory, antitumor, antidiabetic, anti-obesity, antibacterial and anti-septic, antifungal, antiviral, leishmanicidal, antiinflammatory, antinociceptive and analgesic, antioxidant, neuroprotective, wound healing, antiallergic, antiangiogenic, antiemetic and anti-nausea, anti-gastric ulcer and oesophagitis, anthelmintic, antimutagenic, antipsychotic, anxiolytic, photoprotective, anti-wrinkle and periodontal tissue regeneration activities. While it was concluded that although M. citrifolia is widely and successfully used for the treatment or prevention of various diseases, it should be consumed carefully, and only after exhaustive studies into its chemical constituen...Continue Reading
References
Oct 1, 1990·Planta medica·C YounosF Mortier
Sep 30, 1993·Cancer Letters·T HiramatsuK Umezawa
Aug 12, 1999·Phytotherapy Research : PTR·A Hirazumi, E Furusawa
Jun 13, 2001·Oncogene·P AngelM Schorpp-Kistner
Jan 25, 2002·Annals of the New York Academy of Sciences·M Y Wang, C Su
Nov 1, 2002·Phytotherapy Research : PTR·Jonel P SaludesAlicia M Aguinaldo
May 22, 2003·Bioorganic & Medicinal Chemistry·Shengmin SangChi-Tang Ho
Dec 12, 2003·Phytotherapy Research : PTR·Eiichi FurusawaJarakae Jensen
Jan 24, 2004·Angiogenesis·Conrad A HornickEugene A Woltering
Dec 29, 2005·Journal of Medicinal Food·Sung-Woo KimYong-Il Hwang
Apr 19, 2006·Phytotherapy Research : PTR·Teerakul Arpornsuwan, Tadsanee Punjanon
Nov 3, 2006·Parasitology International·D SerenoA Ouaissi
Nov 28, 2006·International Journal of Food Sciences and Nutrition·Isabella CalzuolaValeria Marsili
Feb 9, 2007·Planta medica·Olivier Potterat, Matthias Hamburger
Feb 27, 2007·Journal of Wound Care·B S NayakD D Ramdath
May 8, 2007·Journal of Natural Products·Toshihiro AkihisaYumiko Kimura
Jun 15, 2007·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·S DengC J Jensen
Dec 8, 2007·Journal of Ethnopharmacology·Afa K PaluLeland White
Mar 19, 2008·Journal of Veterinary Internal Medicine·M SchäferB J Darien
May 3, 2008·Biological & Pharmaceutical Bulletin·Kohei KamiyaToshiko Satake
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·B Shivananda NayakAnderson Maxwell
Nov 21, 2008·Journal of Food Science·M S Pak-DekC S Soh
Mar 3, 2009·Biological & Pharmaceutical Bulletin·Shinichi HaradaShogo Tokuyama
Mar 14, 2009·Journal of Natural Medicines·Brett J WestC Jarakae Jensen
Jun 24, 2009·Phytotherapy Research : PTR·Simla BasarJohannes Westendorf
Jul 9, 2009·Phytotherapy Research : PTR·P MuralidharanG Balamurugan
Sep 1, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Aree JainkittivongRobert P Langlais
Oct 8, 2009·Chemistry Central Journal·Mian-Ying WangBrett J West
Nov 13, 2009·Cell Biochemistry and Function·Elif Ilkay TaşkinEngin Ulukaya
Dec 31, 2009·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Danilo R Barros BritoManoel L da Silva Filho
Apr 9, 2010·Indian Journal of Pharmaceutical Sciences·P SelvamJ Neyts
Apr 27, 2010·Physiology & Behavior·Junko MutoToshio Mikami
Jun 25, 2010·Journal of Natural Medicines·Shinichi HaradaShogo Tokuyama
Jul 22, 2010·Pharmaceutical Biology·Smita Nayak, Sushma Mengi
Aug 24, 2010·Lipids in Health and Disease·Saf-ur Rehman MandukhailAnwarul-Hassan Gilani
Sep 23, 2010·Journal of Ethnopharmacology·E DussossoyA Michel
Sep 30, 2010·Phytotherapy Research : PTR·Afa PaluJarakae Jensen
Oct 29, 2010·Evidence-based Complementary and Alternative Medicine : ECAM·B Shivananda NayakAndrew Adogwa
Dec 18, 2010·Journal of Ethnopharmacology·Sirima MahattanadulSrirat Kasiwong
Jan 8, 2011·Biological & Pharmaceutical Bulletin·Kanako OkusadaShogo Tokuyama
May 10, 2011·Journal of Medicinal Food·Mairim Russo SerafiniAdriano Antunes de Souza Araújo
Aug 20, 2011·The Journal of Nutritional Biochemistry·Thararat NualsanitSeung Joon Baek
Oct 18, 2011·Inflammation & Allergy Drug Targets·Thararat NualsanitSeung Joon Baek
Oct 21, 2011·The British Journal of Nutrition·Pratibha V NerurkarVivek R Nerurkar
Nov 24, 2011·Journal of Ethnopharmacology·Shakti Deep PachauriAnil Kumar Dwivedi
Feb 2, 2012·Natural Product Research·Hooi-Kheng BehZhari Ismail
Jan 1, 2009·Journal of Dietary Supplements·Brian F IssellAdrian A Franke
Mar 28, 2012·Asian Pacific Journal of Tropical Medicine·Suthagar Pillai PiaruZeyad Daoud Mahmoud Nassar
May 24, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·William P ClafshenkelPaula A Witt-Enderby
Sep 8, 2012·Plant Foods for Human Nutrition·Yi-Ling LinYi-Chen Chen
Citations
Apr 12, 2018·Foods·Brett J WestClaude Jarakae Jensen
Nov 10, 2018·Journal of Medicinal Food·Cleber da Silveira TorresHaydee Maria Moreira
Dec 13, 2019·Food & Function·Xiaobing YangXiaoyong Wu
Apr 22, 2020·Food & Function·Xiaobing YangXiaoyong Wu
May 13, 2020·Stem Cell Reviews and Reports·Sara AyoubMohammad Fayyad-Kazan
Jul 20, 2018·BMC Research Notes·Fernando Almeida-SouzaKátia da Silva Calabrese
Jul 30, 2019·Journal of Food Biochemistry·Wan NurFarahin Wan OsmanSuhaila Mohamed
Jul 1, 2019·Comprehensive Reviews in Food Science and Food Safety·Édipo S AlmeidaDachamir Hotza
Dec 29, 2020·Mitochondrial DNA. Part B, Resources·Ying-Feng Niu, Jin Liu