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One-pot synthesis of highly functionalized seleno amino acid derivatives

Chemical Biology & Drug Design

Sep 1, 2009

Hai-Xia Liu, Alexander S S Dömling

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Abstract

We herein provide a new and rapid protocol to generate derivatives of seleno amino acid, including methyl selenocysteine, selenomethionine, and selenocystine. Applying the isocyanide-based multicomponent reaction Ugi-4C-5C reaction, we show that each of the commercially available seleno...read more

Mentioned in this Paper

Selenium supplement
Amino Acid [EPC]
Selenomethionine, (S)-Isomer
Amino acid derivative
Selenocystine
Isocyanides
Selenocysteine, DL-Isomer
Selenium Measurement
Selenomethylselenocysteine
Antifibrinolytic amino acids
Paper Details
References
  • References18
  • Citations6
12

One-pot synthesis of highly functionalized seleno amino acid derivatives

Chemical Biology & Drug Design

Sep 1, 2009

Hai-Xia Liu, Alexander S S Dömling

PMID: 19703033

DOI: 10.1111/j.1747-0285.2009.00854.x

Abstract

We herein provide a new and rapid protocol to generate derivatives of seleno amino acid, including methyl selenocysteine, selenomethionine, and selenocystine. Applying the isocyanide-based multicomponent reaction Ugi-4C-5C reaction, we show that each of the commercially available seleno...read more

Mentioned in this Paper

Selenium supplement
Amino Acid [EPC]
Selenomethionine, (S)-Isomer
Amino acid derivative
Selenocystine

Related Papers

Paper Details
References
  • References18
  • Citations6
12

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