One-Step Facile Synthesis of Highly Magnetic and Surface Functionalized Iron Oxide Nanorods for Biomarker-Targeted Applications.

ACS Applied Materials & Interfaces
Anamaria OrzaHui Mao

Abstract

We report a one-step method for facile and sustainable synthesis of magnetic iron oxide nanorods (or IONRs) with mean lengths ranging from 25 to 50 nm and mean diameters ranging from 5 to 8 nm. The prepared IONRs are highly stable in aqueous media and can be surface functionalized for biomarker-targeted applications. This synthetic strategy involves the reaction of iron(III) acetylacetonate with polyethyleneimine in the presence of oleylamine and phenyl ether, followed by thermal decomposition. Importantly, the length and diameter as well as the aspect ratio of the prepared IONRs can be controlled by modulating the reaction parameters. We show that the resultant IONRs exhibit stronger magnetic properties compared to those of the widely used spherical iron oxide nanoparticles (IONPs) at the same iron content. The increased magnetic properties are dependent on the aspect ratio, with the magnetic saturation gradually increasing from 10 to 75 emu g-1 when increasing length of the IONRs, 5 nm in diameter, from 25 to 50 nm. The magnetic resonance imaging (MRI) contrast-enhancing effect, as measured in terms of the transverse relaxivity, r2, increased from 670.6 to 905.5 mM-1 s-1, when increasing the length from 25 to 50 nm. When appl...Continue Reading

References

May 19, 2005·Journal of the American Chemical Society·Sang Jun SonSang Bok Lee
Dec 5, 2008·Journal of the American Chemical Society·Chun-Jiang JiaJörg Raabe
Sep 8, 2011·Journal of the American Chemical Society·Shaojun GuoShouheng Sun
Jun 12, 2013·Proceedings of the National Academy of Sciences of the United States of America·Poornima KolharSamir Mitragotri
Aug 6, 2013·International Journal of Molecular Sciences·Arati G KolhatkarT Randall Lee
Aug 12, 2014·Accounts of Chemical Research·Millicent LinHsian-Rong Tseng
Sep 3, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jing HuangHui Mao
Feb 3, 2015·Advanced Healthcare Materials·Sourabh ShuklaNicole F Steinmetz
Jun 30, 2015·Angewandte Chemie·Adriana Mendoza-GarciaShouheng Sun
Jul 4, 2015·Nanomedicine·Saheel BhanaXiaohua Huang
Aug 13, 2015·Current Drug Metabolism·Salman KhanMohd Sajid Khan
Sep 18, 2015·Theranostics·Oliviero L GobboAdriele Prina-Mello
Dec 29, 2015·Nanomedicine : Nanotechnology, Biology, and Medicine·Zahra BakhtiaryMorteza Mahmoudi
May 25, 2016·Biochimica Et Biophysica Acta. General Subjects·Irena MilosevicMarie-Louise Saboungi
May 31, 2016·The Journal of Physical Chemistry. C, Nanomaterials and Interfaces·Elyahb Allie KwizeraXiaohua Huang
Jun 23, 2016·Chemical Communications : Chem Comm·Dehua XiongLifeng Liu
Jun 28, 2016·ACS Applied Materials & Interfaces·Hai HahamShlomo Margel
Jul 5, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Chen ShiMarc Schneider

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Citations

Apr 5, 2020·International Journal of Molecular Sciences·Raquel G D AndradeElisabete M S Castanheira
Sep 3, 2020·Beilstein Journal of Nanotechnology·Andrey V ShibaevOlga E Philippova
Oct 3, 2019·Materials·Jeotikanta MohapatraJ Ping Liu
Jan 19, 2020·Journal of Photochemistry and Photobiology. B, Biology·Shaheen QasimMurtaza Hasan

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