One-to-many propensity score matching in cohort studies

Pharmacoepidemiology and Drug Safety
Jeremy A RassenSebastian Schneeweiss

Abstract

Among the large number of cohort studies that employ propensity score matching, most match patients 1:1. Increasing the matching ratio is thought to improve precision but may come with a trade-off with respect to bias. To evaluate several methods of propensity score matching in cohort studies through simulation and empirical analyses. We simulated cohorts of 20,000 patients with exposure prevalence of 10%-50%. We simulated five dichotomous and five continuous confounders. We estimated propensity scores and matched using digit-based greedy ("greedy"), pairwise nearest neighbor within a caliper ("nearest neighbor"), and a nearest neighbor approach that sought to balance the scores of the comparison patient above and below that of the treated patient ("balanced nearest neighbor"). We matched at both fixed and variable matching ratios and also evaluated sequential and parallel schemes for the order of formation of 1:n match groups. We then applied this same approach to two cohorts of patients drawn from administrative claims data. Increasing the match ratio beyond 1:1 generally resulted in somewhat higher bias. It also resulted in lower variance with variable ratio matching but higher variance with fixed. The parallel approach gene...Continue Reading

References

Dec 1, 1976·American Journal of Epidemiology·O S Miettinen
Feb 12, 1998·Annals of Internal Medicine·D B Rubin
Jan 30, 2008·Journal of Clinical Epidemiology·Til StürmerJerry Avorn
Mar 19, 2008·Nursing Research·Srichand JastiEva Goldwater
Apr 1, 2010·Pharmacoepidemiology and Drug Safety·M Alan BrookhartSebastian Schneeweiss

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Citations

Mar 1, 2013·The New England Journal of Medicine·Björn PasternakAnders Hviid
Nov 22, 2015·The American Journal of Medicine·Kasper Søltoft LarsenJesper Hallas
Jun 6, 2013·Current Medical Research and Opinion·Keith L DavisWenhui Wei
Mar 1, 2014·The American Journal of Cardiology·Rhonda Bentley-LewisRavi Thadhani
Apr 2, 2013·The Journal of Thoracic and Cardiovascular Surgery·Brian T BatemanNiteesh K Choudhry
Oct 2, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Steven M Brunelli, Jeremy A Rassen
Nov 11, 2015·Journal of the International Neuropsychological Society : JINS·Robert S WilsonDavid A Bennett
Aug 6, 2013·Journal of Evaluation in Clinical Practice·Ariel Linden, Steven J Samuels
May 11, 2012·Pharmacoepidemiology and Drug Safety·Sebastian SchneeweissScott R Smith
Sep 12, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·B T BatemanM A Fischer
Jun 4, 2014·Respirology : Official Journal of the Asian Pacific Society of Respirology·Elizabeth J Williamson, Andrew Forbes
Jan 28, 2014·Health Services Research·M Sanni AliOlaf H Klungel
Jun 4, 2013·Epilepsy Research·Ryan N HansenSean D Sullivan
Apr 23, 2016·Neurology. Clinical Practice·Tim SpelmanHelmut Butzkueven
Dec 3, 2014·Cancer Epidemiology·David GaistHenrik Toft Sørensen
Dec 24, 2014·The American Journal of Medicine·Seoyoung C KimSebastian Schneeweiss
Jun 29, 2015·Social Science & Medicine·Lorraine T DeanIchiro Kawachi
Jul 16, 2013·American Journal of Obstetrics and Gynecology·Brian T BatemanJerry Avorn
May 20, 2015·Anesthesia and Analgesia·Rebecca L JohnsonTerese T Horlocker
Mar 26, 2015·Zeitschrift für Rheumatologie·A Strangfeld, A Richter
Aug 26, 2014·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Mehul R DalalAndres DiGenio
Jan 5, 2016·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R W LaingP Muiesan
Jan 14, 2017·Nature Reviews. Neurology·Maria TrojanoHelmut Butzkueven
Dec 4, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Siddharth SinghTine Jess
Mar 3, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Elaine W YuSeoyoung C Kim
Mar 28, 2017·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·T L ZakrisonV A McCredie

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