One-year clinical outcome with a novel self-expanding transcatheter heart valve

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Costanza PellegriniOliver Husser

Abstract

To evaluate 1-year outcome using the ACURATE neo (Symetis S.A., a Boston Scientific Company, Ecublens, Switzerland) according to the updated Valve Academic Research Consortium (VARC-2) with emphasis on the composite endpoints "clinical efficacy after 30 days" and "time-related valve safety". Initial reports on the clinical performance of patients treated with the ACURATE neo are promising; however, information regarding one-year outcome is scarce, especially with regard to the composite endpoints proposed by the VARC-2. One hundred and fifty one consecutive patients undergoing transfemoral transcatheter aortic valve replacement (TAVR) with the ACURATE neo for severe aortic valve stenosis were enrolled. Data were prospectively collected and event rates during follow-up were calculated as the Kaplan-Meier estimates. Mean age was 81.1 ± 5.9 years and 49.7% (75/151) were female with a median logistic EuroScore of 13.8% [8.2-20.5]. Device success was achieved in 88.1% (133/151) and procedure related mortality was 0.7% (1/151). At one-year, all-cause mortality was 3.3% (5/151), while permanent pacemaker implantation occurred in 12.7% (19/151) of patients. The "clinical efficacy after 30 days" was observed in 24.8% (37/151), where the...Continue Reading

References

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Citations

May 3, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Costanza PellegriniChristian Hengstenberg
Nov 19, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Ashok Seth, Vijay Kumar
Sep 5, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nynke H KooistraPieter R Stella
Aug 10, 2020·Current Cardiology Reports·Taishi OkunoThomas Pilgrim
Mar 19, 2021·Future Cardiology·Jan-Erik GuelkerOliver Husser
Jun 21, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Helge MöllmannWon-Keun Kim

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Methods Mentioned

BETA
sedation

Clinical Trials Mentioned

NCT02987894

Software Mentioned

R
MORENA
riverplot
SPSS Statistics
OsiriX MD
SPSS
ACURATE

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