One-year course and predictors of outcome of adolescent depression: a case-control study in Finland

The Journal of Clinical Psychiatry
Linnea KarlssonMauri Marttunen

Abstract

Clinical studies on the outcome of adolescent depression beyond treatment trials are scarce. To investigate the impact of characteristics of the depressive episode and current comorbidity on the 1-year outcome of depression. A sample of 174 consecutive adolescent psychiatric outpatients (aged 13 through 19 years) and 17 school-derived matched controls, all with unipolar depressive disorders at baseline, were reinterviewed for DSM-IV Axis I and Axis II disorders at 12 months. The study was conducted between January 1998 and May 2002. The outpatients had equal recovery rate and episode duration but shorter time to recurrence than the controls. Among the outpatients, Axis II comorbidity predicted shorter time to recurrence (p = .02). Longer time to recovery was predicted by earlier lifetime age at onset for depression (p = .02), poor psychosocial functioning (p = .003), depressive disorder diagnosis (p <or= .05), and longer episode duration by study entry (p = .001), with an interaction between episode duration and depressive disorder diagnosis (p = .04). Characteristics of depression generally predicted the outcome better than co-morbidity. Axis II comorbidity has prognostic value in adolescent depression.

Citations

Jan 7, 2014·Depression and Anxiety·Klaas J WardenaarPeter de Jonge
Oct 12, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·L SuomalainenM Marttunen
Dec 7, 2016·The Journal of Nervous and Mental Disease·Thea StrandholmMauri Marttunen
Jan 27, 2011·Journal of Traumatic Stress·Henna HaravuoriMauri Marttunen
Feb 20, 2016·The Journal of Nervous and Mental Disease·Thea StrandholmMauri Marttunen
Jan 21, 2015·BMC Psychiatry·Anna S UrrilaUNKNOWN Adolescent Depression Study group
Nov 7, 2019·European Child & Adolescent Psychiatry·Anna S UrrilaUNKNOWN Adolescent Depression Study Group

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