One-year impact of bariatric surgery on serum anti-Mullerian-hormone levels in severely obese women

Journal of Assisted Reproduction and Genetics
Clara VincentelliBlandine Courbiere

Abstract

Although bariatric surgery seems to increase spontaneous fertility by improving ovulatory function in young women, its impact on ovarian reserve remains largely unknown. To evaluate changes in serum anti-Mullerian hormone (AMH) levels in reproductive-age severely obese women after bariatric surgery (BS). AMH levels were measured retrospectively in 39 women (mean age 34.6 ± 1.1 years, range 18-45) that underwent a sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB) at baseline, and 6 and 12 months after BS. Metabolic and micronutrient status, including fasting plasma insulin and glucose, HOMA-IR, leptin, adiponectin, calcium, albumin, transthyretin, ferritin, vitamins (B9, B12, B1, A, E, D), zinc, and selenium, were assessed in all patients before and 1 year after BS. Of the patients, 79% had class-3 obesity. At 6 and 12 months, mean total weight losses (TWL) were 26 and 30%; mean excess weight losses (EWL) were 61.7 and 70.2%. Compared to baseline, AMH levels significantly decreased by 18% at 6 months, and 32% at 12 months post-operatively (p = 0.010 and p = 0.001, respectively). There was no correlation between AMH variation and changes in metabolic parameters or micronutrient levels. Remarkably, changes in AMH levels did no...Continue Reading

References

Nov 3, 2005·Reproduction : the Official Journal of the Society for the Study of Fertility·M MitchellR J Norman
Aug 31, 2007·Fertility and Sterility·Zaher O MerhiDavid B Seifer
Oct 3, 2008·Fertility and Sterility·Dana RochesterNanette Santoro
Jul 2, 2009·Human Reproduction Update·I CetinS Calabrese
Jul 11, 2009·Endocrine Reviews·F J BroekmansB C Fauser
Oct 15, 2009·Obesity Surgery·Edilson João CabreraDecio Sabbatini Barbosa
Oct 31, 2009·Diabetes Care·John B BuseM Sue Kirkman
Jul 27, 2011·PloS One·Thomas W KelseyW Hamish B Wallace
Nov 8, 2011·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Mario MusellaFrancesco Milone
Dec 27, 2011·Reproductive Biomedicine Online·Nathalie SermondadeRachel Lévy
Apr 27, 2012·Reproductive Sciences·Leonardo Oliveira Reis, Fernando Goulart Fernandes Dias
Oct 2, 2013·Obesity Surgery·M FriedUNKNOWN European Association for the Study of Obesity Obesity Management Task Force (EASO OMTF)
Nov 1, 2013·Human Reproduction Update·Alexander N ComninosWaljit S Dhillo
Jan 17, 2014·Human Reproduction Update·Didier DewaillyRichard A Anderson
Apr 20, 2014·The Journal of Clinical Endocrinology and Metabolism·Eun Mi ChangWoo Sik Lee
Jun 17, 2014·Fertility and Sterility·Mohamad Irani, Zaher Merhi
Aug 16, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Nicolas GalazisKypros H Nicolaides
Oct 6, 2015·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine
Oct 16, 2015·The Journal of Clinical Endocrinology and Metabolism·E DirinckL F Van Gaal
Dec 17, 2015·Cell Metabolism·Ida DonkinRomain Barrès
Apr 19, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Shilpa BhandariArun Mishra
Aug 29, 2016·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Geltrude Mingrone, David E Cummings
Mar 16, 2017·Fertility and Sterility·Darcy E Broughton, Kelle H Moley
Apr 4, 2017·Fertility and Sterility·James R CraigJames M Hotaling
Oct 20, 2017·JAMA : the Journal of the American Medical Association·Anne Z SteinerDonna D Baird

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Citations

Nov 26, 2019·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·K MaslinJ Shawe
Apr 15, 2019·European Journal of Nutrition·Carla Bruna PietrobonMaria Lúcia Bonfleur
Jan 23, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Vincenzo PiloneLuigi Schiavo
Apr 25, 2020·International Journal of Environmental Research and Public Health·Pia JägerMetin Senkal
Mar 18, 2021·Obesity Surgery·Lillian DongKen Wing-King Loi
Aug 14, 2021·Human Reproduction Update·Katinka M SnoekSam Schoenmakers
Dec 9, 2021·Wiener klinische Wochenschrift·Dragan D MicicSnezana P Polovina

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