PMID: 30156536Aug 30, 2018Paper

One year in review 2018: Sjögren's syndrome

Clinical and Experimental Rheumatology
Ourania D ArgyropoulouChiara Baldini

Abstract

Sjögren's syndrome is a complex and potentially disabling slow progressive, systemic disorder. During the last twelve months several original and important contributions have been published on the pathogenesis, diagnosis and therapy of the disease. This review, following the others of this series is aimed at summarising some of the most significant studies that have been recently published. Regarding the pathogenesis, we will specifically focus on novel insights on miRNA, gut microbiota, adaptive and innate autoimmunity and animal models. Concerning novelties in pSS diagnosis, we will focus on salivary gland ultrasonography and histology. Finally, we will conclude with an update of the clinical manifestations of the disease and with an overview of the future therapies.

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Clinical and Experimental Rheumatology
Elena ElefanteChiara Baldini
The American Journal of Medicine
S S Kassan, M Gardy
Clinical and Experimental Rheumatology
Francesco FerroElena Bartoloni-Bocci
© 2022 Meta ULC. All rights reserved