One-year interim follow-up results of the TRAVERCE trial: the initial feasibility study for trans-apical aortic-valve implantation

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Thomas WaltherGerhard Wimmer-Greinecker

Abstract

To evaluate the interim results of the initial multicenter feasibility trial for trans-apical aortic-valve implantation (TA-AVI) in high-risk elderly patients with severe aortic stenosis. A total of 168 patients were prospectively included in three European centers between February 2006 and April 2008. The Cribier-Edwards or Edwards SAPIEN™ Trans-catheter Heart Valve (23 mm and 26 mm) was implanted using an oversizing concept. Interventions were performed in a hybrid operative room (OR) (one center), with a mobile C-arm in the OR (one) and in the catheterization laboratory (one). Inclusion criteria included age ≥70 years and an increased risk profile (additive European System for Cardiac Operative Risk Evaluation (EuroSCORE) ≥9). Patient age was 82.1±5.6 years, 76% were female and the EuroSCORE was 11.3±1.8 (additive) and 27±12.7% (logistic). Cardiopulmonary bypass was used by intention in 14.2% during the initial phase, secondarily in 10.1% and 75% of the patients were treated off-pump. Valve implantation led to a good immediate result in 161 (95.8%) patients and problems were encountered in seven patients (malposition (two patients), migration (three patients) and severe incompetence (two patients)). Nine patients were conver...Continue Reading

Citations

Jan 25, 2013·General Thoracic and Cardiovascular Surgery·Takahiro Nishida, Ryuji Tominaga
Mar 27, 2012·The New England Journal of Medicine·Susheel K KodaliUNKNOWN PARTNER Trial Investigators
Mar 10, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jörg KempfertThomas Walther
Apr 24, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Olaf WendlerThomas Walther
May 20, 2014·Progress in Cardiovascular Diseases·Henrique Barbosa RibeiroJosep Rodés-Cabau
Nov 2, 2012·Journal of Thrombosis and Thrombolysis·Jochen ReinöhlManfred Zehender
Mar 22, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Stephan HaussigAxel Linke
Feb 22, 2011·The International Journal of Cardiovascular Imaging·Thomas J HeltonE Murat Tuzcu
Mar 30, 2013·The Journal of Thoracic and Cardiovascular Surgery·Adil H Al KindiLars G Svensson
Sep 17, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Sameer GafoorHorst Sievert
Jan 10, 2012·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Camille HauvilleRon Waksman
Apr 29, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Veronica BonaMartyn Thomas
Feb 5, 2013·Journal of the American College of Cardiology·Philippe GénéreuxMartin B Leon
Aug 12, 2014·Journal of Thrombosis and Thrombolysis·Abhishek SharmaJason Lazar
Dec 17, 2011·The Journal of Thoracic and Cardiovascular Surgery·Antonio Maria CalafioreHoussein Al Amri
Apr 24, 2012·Archives of Cardiovascular Diseases·Thomas WaltherFriedrich W Mohr
Dec 20, 2011·Journal of the American College of Cardiology·Ignacio J Amat-SantosEric Dumont
Jul 16, 2014·Expert Review of Cardiovascular Therapy·Mohamed El-MawardyGert Richardt
Nov 16, 2011·Nature Reviews. Cardiology·Josep Rodés-Cabau
Aug 31, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Jonas LanzStephan Windecker
Apr 22, 2020·International Journal of Technology Assessment in Health Care·Anne-Pauline ThivilliersNicolas Martelli
Jul 16, 2011·The Journal of Cardiovascular Nursing·Marion E McRae, Marnie Rodger
Dec 20, 2012·Expert Review of Medical Devices·Melanie Freeman, John G Webb
Jan 21, 2015·Coronary Artery Disease·Jean-Michel ParadisJosep Rodés-Cabau
May 24, 2017·European Heart Journal Supplements : Journal of the European Society of Cardiology·Francesco BedogniLuca Testa
Dec 18, 2013·Journal of Cardiac Surgery·Amedeo PergoliniFrancesco Musumeci
Feb 9, 2013·Postgraduate Medicine·Estella M DavisThomas M Baker
Aug 12, 2014·Expert Review of Medical Devices·Sa'ar Minha, Ron Waksman
Sep 17, 2014·Expert Review of Cardiovascular Therapy·Igor VolodarskyJacob George

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