One-year mortality rates in US children with end-stage renal disease

American Journal of Nephrology
Blanche M ChaversAllan J Collins

Abstract

Few published data describe survival rates for pediatric end-stage renal disease (ESRD) patients. We aimed to describe one-year mortality rates for US pediatric ESRD patients over a 15-year period. In this retrospective cohort study, we used the US Renal Data System database to identify period-prevalent cohorts of patients aged younger than 19 for each year during the period 1995-2010. Yearly cohorts averaged approximately 1,200 maintenance dialysis patients (60% hemodialysis, 40% peritoneal dialysis) and 1,100 transplant recipients. Patients were followed for up to 1 year and censored at change in modality, loss to follow-up, or death. We calculated the unadjusted model-based mortality rates per time at risk, within each cohort year, by treatment modality (hemodialysis, peritoneal dialysis, transplant) and patient characteristics; percentage of deaths by cause; and overall adjusted odds of mortality by characteristics and modality. Approximately 50% of patients were in the age group 15-18, 55% were male, and 45% were female. The most common causes of ESRD were congenital/reflux/obstructive causes (55%) and glomerulonephritis (30%). One-year mortality rates showed evidence of a decrease in the number of peritoneal dialysis pati...Continue Reading

Citations

Oct 16, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Danilo LofaroJaap W Groothoff
Dec 26, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Sarah J KizilbashBlanche M Chavers
Nov 6, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Julia ThumfartClaus Peter Schmitt
Nov 23, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Keia R Sanderson, Bradley A Warady
Dec 18, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Dinara B GaliyevaNynke Halbesma
Aug 29, 2017·Transplantation·Blanche M ChaversSrinath Chinnakotla
Jan 12, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Shaimaa RakhaNashwa Hamdy
Jul 1, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Sarah J KizilbashBlanche M Chavers
Mar 8, 2019·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Katrin LübbeJörg Dötsch
May 17, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nicholas C ChesnayeKitty J Jager
Aug 25, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Keia R SandersonBradley A Warady
Aug 15, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Bianca Borchert-MörlinsAnette Melk
Jun 27, 2019·Clinics·Maria Luiza do ValPaulo Koch-Nogueira
Jul 10, 2019·Journal of the American Heart Association·Isa F AshoorUNKNOWN CureGN Consortium
Jun 3, 2017·Pediatric Radiology·Aris OatesJesse L Courtier
Feb 6, 2020·Transplantation·Sarah J KizilbashBlanche M Chavers
Jan 20, 2021·Current Opinion in Nephrology and Hypertension·Anne M Kouri, Michelle N Rheault
Jan 24, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Marjolein BonthuisJérôme Harambat
Jun 7, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ryoko HaradaKenji Ishikura

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