One-year outcome after neurosurgery for intracranial tumor in elderly patients

Journal of Neurosurgical Anesthesiology
Romain PirracchioDidier Payen

Abstract

The number of elderly patients proposed for brain tumor removal is increasing. Only few data on long-term functional prognosis after intracranial surgery are available. Prospective, observational study of all patients greater than 70 year of age operated for intracranial tumors. Two scales for health status evaluation were used: Karnofsky Performance Scale (KPS) and Activities of Daily Living (ADL) score. Data were expressed as medians (first to third quartiles). The primary endpoint was the probability to remain nondependant (ADL>3 and KPS≥70%) after 1 year. Between 2003 and 2007, 90 patients were included: 46 (51.1%) meningioma, 17 (18.9%) high-grade glioma, and 11 (12.2%) metastasis. At hospital admission, age was 73.50 years (71.25-76.00), American Society of Anesthesiology score 2 (2 to 3), KPS 80% (70-90), ADL 5.5 (4.5 to 6.0). Two patients died during the first 28 days, 3 others during the first year. Both KPS and ADL decreased after 1 year: KPS 80% (70 to 90; mean: 80%) at hospital admission versus 80% (60 to 90) at 1 year (mean: 70%), P=0.003; ADL 5.5 (4.5 to 6.0) at hospital admission versus 5.0 (3.25 to 5.50) at 1 year, P=0.001. In multivariate analysis, 2 preoperative parameters were associated with autonomy at 1 ye...Continue Reading

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Citations

Dec 3, 2011·Neurosurgical Focus·Wajd N Al-HolouCormac O Maher
Nov 21, 2015·World Neurosurgery·Kathrin Joanna WhitehousePeter C Whitfield
Jun 26, 2012·Acta Neurologica Scandinavica·A KonglundT R Meling
Oct 1, 2013·British Journal of Neurosurgery·Michael Tin-Chung PoonGilberto Ka-Kit Leung
May 17, 2019·Scientific Reports·Christopher Munoz-BendixMarcel A Kamp
Apr 3, 2018·Neurosurgical Focus·Manish KolakshyapatiUNKNOWN Alumni Association Group of the Department of Neurosurgery at Hiroshima University
Feb 13, 2018·European Geriatric Medicine·K Mariam SlotSaskia M Peerdeman
Aug 19, 2017·Neurologia Medico-chirurgica·Fusao IkawaKaoru Kurisu
May 8, 2020·Neurosurgical Review·Silvia SchiavolinMatilde Leonardi
Feb 15, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·John J Y ZhangVincent D W Nga
Oct 1, 2019·World Neurosurgery·Emily R BlighYahia Z Al-Tamimi

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