Ongoing cirrhosis after successful porticoenterostomy in infants with biliary atresia.

Journal of Pediatric Surgery
R P AltmanJ R Lilly

Abstract

Thirty-one patients were treated by portoenterostomy procedures for extrahepatic biliary atresia. In 20, there was unequivocal evidence of bile drainage. Eleven of these 20 were restudied from 3 to 23 mo postoperatively by liver biopsy. The clinical condition of most of these infants was satisfactory. Despite absence of clinical jaundice, normal rose bengal scan, and normal liver function studies, eight showed progressive degrees of hepatic fibrosis when compared to the results of the biopsy taken at the time of portoenterostomy. Two patients showed stable histology and one, after progressing on a second biopsy, had normal liver histology on a third study. The implications of progressive hepatic histopathology despite bile drainage are discussed.

References

Jun 1, 1974·Journal of Pediatric Surgery·D P CampbellE I Smith

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Citations

Sep 1, 1978·World Journal of Surgery·J E Haas
Apr 1, 1985·World Journal of Surgery·M CheneyJ R Lilly
Jan 1, 1989·Pediatric Radiology·D L DayJ G Letourneau
Mar 1, 1983·Indian Journal of Pediatrics·M Kasai, R Ohi
Oct 3, 2003·Journal of Pediatric Surgery·Abdurrahman KaramanIclal Gürses
Aug 1, 1984·Journal of Pediatric Surgery·J R Lilly, G Stellin
Feb 1, 1997·Journal of Pediatric Surgery·K S AzarowR A Superina
Jun 26, 2001·Liver·R Ohi
Sep 1, 1976·Annals of Surgery·J R Lilly, N B Javitt
Mar 1, 1979·Australian Paediatric Journal·A P Mowat
Nov 1, 1977·Archives of Disease in Childhood·E R Howard, A P Mowat
Nov 1, 1980·Archives of Disease in Childhood·H T PsacharopoulosA P Mowat
Jan 1, 1989·Baillière's Clinical Gastroenterology·K C Tan, E R Howard
Apr 1, 1990·Journal of Pediatric Surgery·R OhiM Ibrahim
Jan 1, 1978·American Journal of Surgery·R P Altman, B M Potter
Jan 1, 1997·The Tohoku Journal of Experimental Medicine·M NioN Sano
Jun 24, 2004·Journal of Pediatric Surgery·Keiichi UchidaMasato Kusunoki
Oct 1, 1990·Journal of Pediatric Surgery·F M KarrerR J Hall
Mar 31, 2001·The American Journal of Gastroenterology·T KunimuraT Morohoshi
Jul 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J B OtteB Debande
Apr 1, 1983·The British Journal of Surgery·E R Howard
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D Alagille
Sep 1, 1978·World Journal of Surgery·M KasaiA Okamoto
Feb 1, 1984·American Journal of Hematology·R A YanofskyW E Hathaway
Sep 1, 1978·World Journal of Surgery·M Odièvre

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