Only the strong survive

Immunity
Andreas Villunger

Abstract

Whether apoptosis is relevant for interclonal competition of T cells after antigen encounter has remained uncertain. In this issue of Immunity, Wensveen et al. (2010) establish a critical role for the proapoptotic BH3-only protein Noxa in this selection process.

Citations

Nov 10, 2010·Immunology and Cell Biology·G Jan WiegersAndreas Villunger
Oct 9, 2013·Nature Reviews. Nephrology·Mandy L FordThomas C Pearson

❮ Previous
Next ❯

Related Concepts

Related Feeds

BCL-2 Family Proteins

BLC-2 family proteins are a group that share the same homologous BH domain. They play many different roles including pro-survival signals, mitochondria-mediated apoptosis and removal or damaged cells. They are often regulated by phosphorylation, affecting their catalytic activity. Here is the latest research on BCL-2 family proteins.

Avian Influenza: Innate Immune Adjuvant

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Avian Influenza: Innate Immune Adjuvant (ASM)

Adjuvants systems that are added to vaccines against avian influenza have be explored to enhance the innate immune system response against the virus. Here is the latest research on avian influenza and the innate immune adjuvant.