Onset and disappearance of reflux symptoms in a Chinese population: a 1-year follow-up study

Alimentary Pharmacology & Therapeutics
W M WongB C Y Wong

Abstract

The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before. To study the onset and disappearances of reflux symptoms over a 1-year period in the Chinese population. A population-based telephone survey was performed in 2002 and repeated 1 year later. The change in prevalence rate, onset and disappearance of gastro-oesophageal reflux disease, and the change in diagnoses were assessed. Factors associated with the onset and disappearance of gastro-oesophageal reflux disease were studied. A total of 712 subjects completed the first and second survey. The annual, monthly and weekly prevalence of gastro-oesophageal reflux disease were 34.1%, 10.1% and 2.7% respectively. The onset rate (per 1000 person-year) and disappearance rate of any gastro-oesophageal reflux disease and frequent gastro-oesophageal reflux disease (> or = monthly symptoms) were 209, 40; and 395, 243 respectively. Forty-four percentage of gastro-oesophageal reflux disease subjects changed their diagnoses in 2003. By multiple logistic regression analysis, high anxiety score (OR: 1.2, 95% CI: 1.1-1.2) and higher educational level (OR: 2.7, 95% CI: 1.3-6.3) were associated with the onset of gastro-oesophageal reflux disease;...Continue Reading

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Jul 29, 2000·Biochemical and Biophysical Research Communications·S BreitL Schweigerer
May 1, 2007·European Journal of Clinical Pharmacology·Juan ZengGuo-Ping Lv
Sep 4, 2013·Best Practice & Research. Clinical Gastroenterology·Jukka Ronkainen, Lars Agréus
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