Ontogenetic changes of craniofacial complex in Turner syndrome patients treated with growth hormone

Clinical Oral Investigations
Jovana JuloskiMarko Babic

Abstract

The present study assessed changes of craniofacial complex in Turner syndrome (TS) patients treated with growth hormone (GH) during development. The objective was to examine the growth rate and pattern of craniofacial structures and to establish effects of GH on craniofacial development. The study population consisted of 15 TS patients treated with GH aged 5-18.5 years (13.3 ± 4.4) and corresponding control group of 45 females aged 6.8-18.7 (11.4 ± 2.6). According to the stage of cervical vertebral maturation, subjects were categorized into pre-growth (5 TS and 15 controls) and growth (10 TS and 30 controls) subgroups. The cephalometric analysis comprised angular and linear variables, measured on lateral cephalometric radiographs. The mandibular corpus/anterior cranial base ratio increased significantly only in controls during development. In growth period, ramus/corpus ratio was significantly larger in TS group. SNA and SNB angles were significantly smaller in TS growth subgroup compared to corresponding controls. Among other variables, no statistically significant differences were revealed. In TS patients treated with GH, growth capacities of cranial base and maxilla are adequate which can be attributed to GH treatment. Shape...Continue Reading

References

Aug 1, 1991·European Journal of Orthodontics·M BabićS Mićić
Oct 1, 1974·Archives of Disease in Childhood·C G BrookA Prader
Feb 1, 1993·Archives of Oral Biology·M BabićM Mićić
Jun 1, 1996·European Journal of Orthodontics·M MidtbøA Halse
Apr 1, 1997·European Journal of Orthodontics·M BabićI Sćepan
Feb 11, 2000·Archives of Oral Biology·M GrönL Alvesalo
Apr 6, 2000·Human Molecular Genetics·M Clement-JonesG A Rappold
May 24, 2000·European Journal of Orthodontics·E AndersenI Kjaer
Jan 3, 2001·Journal of Medical Genetics·T OgataG Nishimura
Jul 10, 2001·The Journal of Clinical Endocrinology and Metabolism·P SaengerUNKNOWN Fifth International Symposium on Turner Syndrome
Jun 8, 2002·Hormone Research·Michael L DavenportVirginia P Sybert
Aug 5, 2004·The Journal of Clinical Endocrinology and Metabolism·C J F MunnsJ A Batch
Mar 4, 2005·European Journal of Orthodontics·Marja R PerkiömäkiLassi Alvesalo
Oct 19, 2006·The Journal of Clinical Endocrinology and Metabolism·Carolyn A Bondy, UNKNOWN Turner Syndrome Study Group
Nov 9, 2006·The Angle Orthodontist·Minayo FunatsuHideo Mitani
Nov 28, 2009·Archives of Oral Biology·J DumancicH Brkic
Nov 11, 2010·Genetics and Molecular Research : GMR·V A DjordjevićM D Gotić

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Citations

Aug 7, 2013·American Journal of Medical Genetics. Part a·Mauren Abreu de SouzaPeter Hammond
Jul 4, 2016·Archives of Oral Biology·Jovana JuloskiMarko Babić
Jul 17, 2016·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Sung-Hwan ChoiChung-Ju Hwang
May 31, 2018·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Angela Pia CazzollaMaria Grazia Lacaita
Feb 13, 2020·Diagnostics·Dorota Wójcik, Iwona Beń-Skowronek

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