Ontogeny of calretinin expression in rat dorsal root ganglia

Brain Research. Developmental Brain Research
A AmbrusI Barakat-Walter

Abstract

The relationship between the expression of calretinin and the maturation level of peripheral sensory neurons was investigated by means of immunohistochemistry and immunoblot analysis. Our immunohistochemical results show that calretinin is expressed during two different developmental phases in rat dorsal root ganglia. The early phase lasts between embryonic days 11 and 14, when calretinin is detectable in the majority (75%) of the cells. A second phase starts at embryonic day 17 and lasts throughout the whole postnatal life, when calretinin is expressed only in a small proportion of the neurons (less than 8%). Between these two periods no calretinin is found in the ganglia. These changes in calretinin expression during embryonic development were confirmed by Western blot analysis. The early expression of calretinin in dorsal root ganglion cells suggests that calretinin may act as a calcium regulator until neurotrophins take over the precise tuning of intracellular calcium concentration.

References

Sep 1, 1992·Trends in Neurosciences·R J Miller
Aug 1, 1992·Trends in Neurosciences·K G BaimbridgeJ H Rogers
Nov 20, 1992·Brain Research. Developmental Brain Research·E Király, M R Celio
Jan 1, 1992·Neuroscience·A Résibois, J H Rogers
Jan 11, 1992·Experimental Neurology·E M JohnsonJ Franklin
Jan 1, 1991·Anatomy and Embryology·S Solbach, M R Celio
Sep 1, 1990·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·J R Glaser, E M Glaser
Jul 1, 1988·Trends in Neurosciences·S B KaterJ Connor
Nov 1, 1989·Trends in Neurosciences·A PersechiniR H Kretsinger
Jan 1, 1987·Anatomy and Embryology·S EnderlinM R Celio
Jan 1, 1970·Histochemie. Histochemistry. Histochimie·M Kalina, M Wolman
Jan 1, 1984·Experimental Neurology·J P Cummings, D J Stelzner
Jul 1, 1995·Trends in Neurosciences·P B SimpsonS R Nahorski
Feb 1, 1993·Cell and Tissue Research·C AndressenM R Celio
Mar 15, 1996·The Journal of Biological Chemistry·M A De BernardiI Mocchetti
May 1, 1997·Trends in Neurosciences·S MartyB Berninger

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Citations

Mar 12, 2008·Brain Research Bulletin·Amaia ViloriaManuel Megías
Oct 29, 2013·Neuroscience·P M MasliukovV P Smirnova
May 27, 2016·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Katarina VukojevicMirna Saraga-Babic

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