Ontogeny of circadian rhythmicity for melatonin, serotonin, and N-acetylserotonin in humans

Journal of Pineal Research
A AttanasioD Gupta

Abstract

The serum concentration of melatonin, serotonin, and N-acetylserotonin were measured by RIA procedures in 28 infants aged 1 week to 9 months. Blood specimens were obtained at 12:00 hr and 24:00 hr. A day-night difference in serum serotonin was present immediately after birth. A significant (P less than 0.001) decrease in serum serotonin concentrations at 12:00 hr and 24:00 hr was observed from the first month of age to the third to ninth month of age. A significant (P less than 0.05) difference in day-night N-acetylserotonin concentration is first seen at age 1-3 months. Serum melatonin concentrations, though detectable, did not show any day-night difference at birth. Melatonin concentrations progressively increased up to the third month of age, and a significant (P less than 0.01) day-night difference appeared thereafter. The results indicate that in humans the circadian organization for serotonin already exists at birth, and the circadian melatonin rhythm develops after birth.

References

Dec 1, 1975·General and Comparative Endocrinology·S Binkley, E B Geller
Apr 1, 1985·Developmental Medicine and Child Neurology·G M AndersonD J Cohen
Aug 1, 1985·The Journal of Clinical Endocrinology and Metabolism·A AttanasioD Gupta
Jun 1, 1969·Endocrinology·D C Klein, S V Lines
May 4, 1981·Life Sciences·D C KleinD A Auerbach

❮ Previous
Next ❯

Citations

May 15, 1992·Experientia·R Wilf-MironI E Ashkenazi
Oct 15, 1989·Experientia·F J Ebling, D L Foster
Mar 1, 1990·Brain Research. Developmental Brain Research·D F SwaabM B Honnebier
Mar 1, 1992·The International Journal of Neuroscience·R Sandyk
Sep 1, 1987·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·R W Rivest
Sep 1, 1996·Journal of Pineal Research·A Molina-CarballoD Acuña-Castroviejo
Sep 24, 1998·Journal of Pineal Research·Y OkataniY Sagara
Jan 24, 2012·Pediatric Neurology·Rūta PraninskienėAurelija Jučaitė
Jul 26, 2011·Molecular and Cellular Endocrinology·Jimo BorjiginAnda-Alexandra Calinescu
Nov 1, 1989·Baillière's Clinical Endocrinology and Metabolism·I C McMillen, R Nowak
Jan 12, 2010·Animal Reproduction Science·A Gómez-BrunetA López-Sebastián
Feb 24, 2016·American Journal of Obstetrics and Gynecology·Alejandro González-CandiaEmilio A Herrera
Oct 13, 2006·BJU International·Julio Ardura-FernandezTeresa Agapito
Jun 19, 2010·Pediatrics International : Official Journal of the Japan Pediatric Society·Hitomi Shinohara, Hideya Kodama
Feb 26, 2005·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Patricia M Whitaker-Azmitia
Sep 18, 1997·Medical Hypotheses·J RecioE Challet
Jul 1, 1992·Medical Hypotheses·M Weissbluth, L Weissbluth
Mar 1, 1990·Forensic Science International : Synergy·W Q SturnerR J Wurtman
Sep 7, 2000·Seminars in Perinatology·D J Kennaway
Jan 3, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Oliviero BruniPaolo Curatolo
Aug 23, 2012·The Journal of Pediatrics·Lucia MarsegliaEloisa Gitto
May 20, 2010·Journal of Pediatric Endocrinology & Metabolism : JPEM·J UberosA Muñoz-Hoyos
May 1, 1996·Journal of Pediatric Endocrinology & Metabolism : JPEM·S MantagosA Vagenakis
May 28, 2010·Journal of Child Neurology·Julio ArduraFrancisco Ardura
May 15, 2013·International Journal of Molecular Sciences·Jie LiuHong-Wen He
Nov 1, 2011·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Yusuf Ozgur Cakmak
Sep 15, 2018·Endocrine Reviews·José Cipolla-Neto, Fernanda Gaspar do Amaral
Mar 10, 2001·The Journal of Clinical Endocrinology and Metabolism·A Muñoz-HoyosD Acuña-Castroviejo
Jan 17, 2017·Journal of Biological Rhythms·Sean LoppCecilia Diniz Behn
Aug 31, 2004·Chronobiology International·Julio ArduraTeresa Agapito
Mar 16, 2019·Journal of Translational Medicine·Susanna EspositoElisabetta Mencaroni
Apr 11, 2000·Chronobiology International·L PelegI Ashkenazi
Mar 24, 1998·Clinical Endocrinology·I Kostoglou-AthanassiouM L Forsling
Feb 9, 2021·Journal of the American Academy of Child and Adolescent Psychiatry·Martijn ArnsAndrew N Coogan
May 31, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Arturo A VitaleJorge Ciprian-Ollivier
Aug 27, 2021·Journal of Pineal Research·Ko-Hsiu LuShun-Fa Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.