Ontogeny of lymphocytes expressing J chain in chickens

Cellular Immunology
O Moriya

Abstract

The ontogeny of chicken lymphocytes expressing J chain (LEJ) was investigated in the embryonic bursa of Fabricius, the spleen, and the thymus. Simultaneous appearance of LEJ was detected in the bursa and spleen on Day 14 of incubation. These cells were detected later in the thymus. The LEJ were found to increase rapidly in the spleen from the 19th to 20th incubation day. In adult chickens, the highest percentage of LEJ was also found in the spleen. These cells were seen in the thymus at a lower frequency. Intermediate numbers were found in bursal and peripheral blood lymphocytes. The frequencies of the LEJ were similar to those of lymphocytes positive for cytoplasmic immunoglobulins (Ig) IgA and IgM, but were not related to the number of lymphocytes expressing surface Ig. It is possible to consider that the suitable site for LEJ is the spleen, on the basis of the rapid increase in the number of LEJ just before hatching and from the fact that the highest value is found in adult chickens. Furthermore, LEJ may participate in secretion of IgA or IgM but not be associated with the expression of surface Ig.

References

Jan 1, 1979·Journal of Immunological Methods·A Lebacq
Jan 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·S L Morrison, M E Koshland

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Citations

Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·G Kelényi
Mar 1, 1993·Developmental and Comparative Immunology·O Moriya, Y Ichikawa
Sep 1, 1987·Veterinary Immunology and Immunopathology·C Moriya
May 1, 1990·Veterinary Immunology and Immunopathology·O Moriya, Y Ichikawa
Jan 1, 1991·Acta histochemica·O Moriya, Y Ichikawa
Jan 1, 1990·Acta histochemica·O Moriya, Y Ichikawa
Jan 1, 1989·Acta histochemica·O Moriya, Y Ichikawa

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