PMID: 7008011Oct 1, 1980Paper

Ontogeny of secretory immunity: levels of secretory IgA and natural antibodies in saliva

Pediatric Research
G R BurgioA G Ugazio

Abstract

In 187 healthy subjects from 2 months to 27 years of age, secretory IgA and free secretory component were assayed in samples of whole saliva obtained before and after stimulation with lemon juice. Antibody titers against Escherichia coli O antigens and against rabbit erythrocytes were also dosed in unstimulated saliva. Secretory IgA, undetectable in newborns, was present in all 2-month-olds tested in both unstimulated and stimulated saliva; thereafter secretory IgA levels increased progressively, reaching adult values by 6 to 8 years in unstimulated saliva and already by 2 to 4 years in stimulated saliva. The antibody titers assessed in unstimulated saliva followed a similar pattern also reaching adult values by 6 to 8 years. On the other hand, free secretory component levels showed no significant variation with age in unstimulated saliva whereas a slight increase was observed in the first year of life in stimulated saliva.

Citations

Jan 1, 1986·Journal of Clinical Immunology·D J SmithJ L Ebersole
Jan 1, 1995·Clinical Reviews in Allergy & Immunology·B A Chowdhury
Oct 7, 2004·Current Allergy and Asthma Reports·Diane E Schuller
Jan 1, 1985·Archives of Oral Biology·L GahnbergJ L Ebersole
Sep 1, 1983·Molecular Immunology·M E ConleyS D Douglas
Apr 23, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Frederick M Schaffer
Oct 1, 1996·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·A MeiniA Plebani
Apr 16, 1999·Oral Microbiology and Immunology·G Hajishengallis, S M Michalek
May 1, 1991·Scandinavian Journal of Immunology·M GleesonM J Hensley
Apr 1, 1990·Oral Microbiology and Immunology·D J SmithM A Taubman
Aug 1, 1994·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·M KailaE Isolauri
Feb 1, 1995·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·M Kuitunen, E Savilahti
Jan 15, 2011·Clinical & Developmental Immunology·Patricia EwingAllan W Cripps
Mar 15, 2013·Journal of Oral Microbiology·Per Brandtzaeg
Sep 22, 2012·ISRN Gastroenterology·Bhoomika K Patel, Jigna S Shah
Jul 1, 1991·Pediatric Hematology and Oncology·G R BurgioA G Ugazio
Jan 1, 1987·Scandinavian Journal of Rheumatology. Supplement·G R Burgio, A Martini
May 15, 2007·Immunology·Liliana BezrodnikGuillermo H Docena
Sep 20, 1993·Annals of the New York Academy of Sciences·M A Taubman, D J Smith
Dec 3, 2014·The American Journal of Pathology·Scott M TannerColin A Martin
Mar 19, 2008·Seminars in Perinatology·Patricia W LinBarbara J Stoll
Jan 1, 1990·Archives of Oral Biology·H Ben-AryehD Laufer
Nov 1, 1986·The Journal of Allergy and Clinical Immunology·W A Walker
May 5, 2004·Best Practice & Research. Clinical Gastroenterology·Karen M PickardThomas T MacDonald
Jan 1, 1988·Archives of Oral Biology·F J Grundbacher
May 1, 1984·Acta paediatrica Scandinavica·N F ButteA S Goldman
Apr 1, 1994·The Journal of Pediatrics·S P FitzsimmonsM F Cole
Jul 1, 1990·The Journal of Pediatrics·J N Udall
Jan 1, 1986·The Journal of Pediatrics·C B Wilson
May 18, 1999·The Journal of Allergy and Clinical Immunology·H A Sampson
Jun 9, 2004·Clinics in Perinatology·Kristina M Reber, Craig A Nankervis
Jan 1, 1995·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J D Rudney
Oct 16, 2015·Journal of Human Lactation : Official Journal of International Lactation Consultant Association·Leah C Hibel, Hillary Schiltz
Feb 1, 1987·Journal of Dental Research·D J SmithJ L Ebersole
Feb 1, 1987·Journal of Dental Research·J TenovuoP Vilja
Nov 26, 2003·Scandinavian Journal of Immunology·C WeemaesA Haraldsson
Aug 25, 2004·FEMS Immunology and Medical Microbiology·Maree Gleeson, Allan W Cripps

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