PMID: 7581625Jun 1, 1995Paper

Ontology-based configuration of problem-solving methods and generation of knowledge-acquisition tools: application of PROTEGE-II to protocol-based decision support

Artificial Intelligence in Medicine
S W TuMark A Musen

Abstract

PROTEGE-II is a suite of tools and a methodology for building knowledge-based systems and domain-specific knowledge-acquisition tools. In this paper, we show how PROTEGE-II can be applied to the task of providing protocol-based decision support in the domain of treating HIV-infected patients. To apply PROTEGE-II, (1) we construct a decomposable problem-solving method called episodic skeletal-plan refinement, (2) we build an application ontology that consists of the terms and relations in the domain, and of method-specific distinctions not already captured in the domain terms, and (3) we specify mapping relations that link terms from the application ontology to the domain-independent terms used in the problem-solving method. From the application ontology, we automatically generate a domain-specific knowledge-acquisition tool that is custom-tailored for the application. The knowledge-acquisition tool is used for the creation and maintenance of domain knowledge used by the problem-solving method. The general goal of the PROTEGE-II approach is to produce systems and components that are reusable and easily maintained. This is the rationale for constructing ontologies and problem-solving methods that can be composed from a set of sma...Continue Reading

References

Oct 1, 1992·Computers and Biomedical Research, an International Journal·M A Musen
Jun 1, 1995·Artificial Intelligence in Medicine·G van HeijstM Stefanelli

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Citations

Feb 10, 2012·Journal of Medical Systems·Biqing HuangCheng Wu
Jun 1, 1995·Artificial Intelligence in Medicine·M A Musen, A T Schreiber
Jun 1, 1995·Artificial Intelligence in Medicine·G van HeijstM Stefanelli
Jul 1, 1996·Artificial Intelligence in Medicine·Y Shahar, M A Musen
Jun 9, 1998·Computer Methods and Programs in Biomedicine·C E Kahn
Jul 27, 2001·Artificial Intelligence in Medicine·A Rector
Mar 7, 2002·Artificial Intelligence in Medicine·T Wetter
Feb 1, 1997·Artificial Intelligence in Medicine·A L RectorW D Solomon
Oct 13, 1999·Artificial Intelligence in Medicine·M TaboadaF Palacios
Sep 9, 2000·International Journal of Medical Informatics·S MontaniM Stefanelli
Dec 6, 2001·International Journal of Medical Informatics·P A de ClercqH H Korsten
Mar 13, 1999·International Journal of Medical Informatics·S MontaniM Stefanelli
Apr 17, 1999·International Journal of Medical Informatics·J Stausberg, M Person
Nov 1, 1996·Journal of the American Medical Informatics Association : JAMIA·M A MusenY Shahar
Aug 18, 2005·BMC Medical Informatics and Decision Making·Timothy J DoyleRichard S Hopkins
Aug 28, 2001·Journal of the American Medical Informatics Association : JAMIA·Y R NgA L Reiss
Dec 1, 1999·Journal of the American Medical Informatics Association : JAMIA·Y ShaharM A Musen
Feb 7, 1998·Journal of the American Medical Informatics Association : JAMIA·C RosseJ F Brinkley
May 1, 1997·Journal of the American Medical Informatics Association : JAMIA·J F Brinkley, C Rosse
Aug 13, 2013·Journal of the American Medical Informatics Association : JAMIA·Jesualdo Tomás Fernández-BreisMontserrat Robles
Jan 21, 2015·JMIR Medical Informatics·Raimundo Lozano-RubíEsther Lozano
May 31, 2016·AI Matters·Mark A Musen, UNKNOWN Protégé Team
Sep 14, 2000·Journal of the American Medical Informatics Association : JAMIA·R B Altman
Nov 1, 2009·Artificial Intelligence for Engineering Design, Analysis and Manufacturing : AI EDAM·Martin J O'ConnorMark A Musen
Jan 1, 2019·Journal of Biomedical Informatics·Alan RectorHarold Solbrig

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