Onychomadesis after hand-foot-and-mouth disease outbreak in northern Greece: case series and brief review of the literature

International Journal of Dermatology
Zoe ApallaDemetris Ioannides

Abstract

Nail abnormalities in childhood are generally uncommon. Recently, onychomadesis was described as a late complication of hand-foot-and-mouth disease (HFMD). Onychomadesis outbreaks following HFMD have been reported in many countries worldwide. To present a case series of onychomadesis in children, following HFMD outbreak in Northern Greece, and review literature data. Children with evident onychomadesis attending the outpatient clinic between November 2012 and January 2013 were included in the study. A questionnaire including demographic personal and family history information of the children was completed by the parents. Patients were clinically examined, and their pediatric and dermatological records were studied to confirm precedent HFMD. Direct microscopic examination and cultures for fungi were performed. Exposure of participants to coxsackievirus, based on serology testing during infection, was also recorded. Sixty-eight children with onychomadesis were included. The mean number of affected nails was 8.82. Fingernails were more often involved. Previous clinical diagnosis of HFMD was confirmed in 67/68 cases. The mean time from HFMD diagnosis to onychomadesis development was 39.6 days (range: 28-56 days, STD: 7.33). Direct ...Continue Reading

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Jan 1, 2011·Case Reports in Dermatological Medicine·Emi ShikumaYoshiki Miyachi

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Citations

Feb 3, 2016·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Wietske A ChristoffersSylvia H Kardaun
Oct 9, 2016·The Journal of Emergency Medicine·Hsiu-Hui ChiuCheng-Che E Lan

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