Open-field study comparing an essential oil-based shampoo with miconazole/chlorhexidine for haircoat disinfection in cats with spontaneous microsporiasis

Journal of Feline Medicine and Surgery
Simona NardoniF Mancianti

Abstract

Objectives The goal of the present study was to compare the antifungal efficacy of an essential oil (EO) shampoo proven to be effective against Microsporum canis with miconazole/chlorhexidine for topical haircoat disinfection in cats treated concurrently with oral itraconazole. Methods Cats received treatment with oral itraconazole (Itrafungol) at a dose of 5 mg/kg/day pulse administration for 1 week, every 2 weeks for at least 6 weeks and were washed twice a week with a neutral shampoo with added EOs of Thymus serpyllum (2%), Origanum vulgare and Rosmarinus officinalis (5% each) for the period of systemic treatment. This protocol was compared with a conventional treatment (oral itraconazole + 2% miconazole/2% chlorhexidine shampoo). Results The treatment was well tolerated and adverse effects were not recorded. All cats were clinically negative at week 11. With respect to animals with extensive lesions, the speed of resolution was higher in cats with focal lesions. The animals showing diffuse lesions required more than a course of treatment to achieve a mycological cure. There was no significant difference between the number of weeks to obtain mycological cure for cats treated with EOs and animals treated conventionally. Concl...Continue Reading

References

Nov 19, 2003·Journal of Feline Medicine and Surgery·F ManciantiC Ponticelli
Mar 20, 2004·Veterinary Dermatology·Karen A Moriello
Feb 27, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Michael Eisenhut
May 15, 2008·Mycopathologia·René ChermetteJacques Guillot
Aug 8, 2008·Journal of Feline Medicine and Surgery·Francesca ManciantiSimona Nardoni
Aug 16, 2014·Veterinary Dermatology·Karen A Moriello
Apr 10, 2015·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Simona NardoniFrancesca Mancianti

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