Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem

Journal of Laboratory Automation
Chenlong ZhangJoshua M Pearce

Abstract

The combination of open-source software and hardware provides technically feasible methods to create low-cost, highly customized scientific research equipment. Open-source 3-D printers have proven useful for fabricating scientific tools. Here the capabilities of an open-source 3-D printer are expanded to become a highly flexible scientific platform. An automated low-cost 3-D motion control platform is presented that has the capacity to perform scientific applications, including (1) 3-D printing of scientific hardware; (2) laboratory auto-stirring, measuring, and probing; (3) automated fluid handling; and (4) shaking and mixing. The open-source 3-D platform not only facilities routine research while radically reducing the cost, but also inspires the creation of a diverse array of custom instruments that can be shared and replicated digitally throughout the world to drive down the cost of research and education further.

References

Sep 24, 2011·Nature Chemistry·Michael WoelfleMatthew H Todd
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Nov 23, 2012·Nature·Joshua M Pearce
Apr 2, 2013·PloS One·Chenlong ZhangJoshua M Pearce
Apr 23, 2013·Sensors·Gerald C AnzaloneJoshua M Pearce
Jan 18, 2014·Analytical Chemistry·Bethany C GrossDana M Spence
Mar 20, 2014·Journal of Proteomics·Mauricio Maldonado-TorresRobert Winkler
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Sep 18, 2014·PloS One·Bas WijnenJoshua M Pearce
Mar 21, 2015·PLoS Biology·Tom BadenThomas Euler
Oct 13, 2015·Journal of Biological Methods·Tulsi R DamasePeter B Allen

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Citations

Aug 30, 2016·Journal of Microscopy·Bas WijnenJoshua M Pearce
Jul 17, 2016·Journal of Laboratory Automation·James M Gill, Alden S Hart
Nov 7, 2017·Sensors·Rocio B DominguezAlfredo Márquez-Lucero
Jun 27, 2019·Lab on a Chip·Hunter BachmanTony Jun Huang
Aug 5, 2017·Materials·Handy ChandraJoshua M Pearce
Feb 13, 2021·Analytical Methods : Advancing Methods and Applications·Héctor Guillén-AlonsoRobert Winkler
Jan 17, 2021·Journal of Chromatography. a·Joshua J DavisJames P Grinias
Aug 14, 2020·Chemical Reviews·Gurpur Rakesh D Prabhu, Pawel L Urban

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Software Mentioned

Libre Office Calc
Opentrons
RepRap
OpenSCAD
OS
Linux
Cura

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