PMID: 26340308DOI: 10.1021/acsnano.5b05161Sep 5, 2015Paper
Opening Windows into Tumors
ACS Nano
Dmitri Simberg
Abstract
Delivery of nanoparticles to tumors is limited by vascular permeability and intratumoral diffusion. In this issue of ACS Nano, Jiang et al. show that the manipulation of tumor physiology using antiangiogenic therapy can improve the tumor penetration of quantum dots with 20 and 40 nm hydrodynamic diameters. This Perspective describes the problems, challenges, and perspectives of using antiangiogenic therapy in combination with nanometer-sized drugs and contrast agents in preclinical and clinical studies.
References
Apr 7, 2000·The American Journal of Pathology·H HashizumeD M McDonald
Feb 22, 2002·International Journal of Cancer. Journal International Du Cancer·Jun WuHiroshi Maeda
Jun 4, 2004·The New England Journal of Medicine·Herbert HurwitzFairooz Kabbinavar
Jan 8, 2005·Science·Rakesh K Jain
Apr 7, 2007·Neurosurgery·Edward A NeuweltJohn M Hoffman
Sep 5, 2007·Cancer Metastasis Reviews·Diane R Bielenberg, Michael Klagsbrun
Dec 18, 2007·Neoplasia : an International Journal for Oncology Research·Mukesh HarisinghaniRalph Weissleder
May 9, 2008·The New England Journal of Medicine·Robert S Kerbel
Apr 7, 2009·Nano Letters·Steven D PerraultWarren C W Chan
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Chung Hang J ChoiMark E Davis
Apr 10, 2010·Science·Kazuki N SugaharaErkki Ruoslahti
Feb 11, 2011·The New England Journal of Medicine·Eric RaymondPhilippe Ruszniewski
Jun 15, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·You Han Bae, Kinam Park
Jun 29, 2011·The New England Journal of Medicine·Ralph B D'Agostino
Sep 29, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·Twan LammersGert Storm
Feb 15, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jonas BerghCarla Giorgetti
Apr 10, 2012·Nature Nanotechnology·Vikash P ChauhanRakesh K Jain
Jun 2, 2012·Nano Letters·Bryan Ronain SmithSanjiv Sam Gambhir
Aug 2, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C F VerschraegenF Muggia
Aug 29, 2012·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·John MoroneyRazelle Kurzrock
Apr 12, 2013·Cancer Research·Barbara SenninoDonald M McDonald
Aug 21, 2013·Biotechnology Advances·L C HullP Grodzinski
Jan 15, 2014·Cancer Research·Piotr Grodzinski, Dorothy Farrell
Jun 17, 2014·Lancet·Edward B GaronMaurice Pérol
Oct 10, 2014·Nature Biotechnology
Jan 22, 2015·Proceedings of the National Academy of Sciences of the United States of America·Rebecca S HeistRakesh K Jain
Feb 12, 2015·Annals of Biomedical Engineering·Triantafyllos StylianopoulosRakesh K Jain
Jul 28, 2015·ACS Nano·Wen JiangBetty Y S Kim
Dec 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C F VerschraegenF Muggia
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Citations
Feb 18, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Benjamin TheekTwan Lammers
Jun 11, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Jiangshan WanHuibi Xu
Jan 8, 2019·Journal of Drug Targeting·Michael J BenchimolDmitri Simberg
Mar 9, 2021·Advanced Materials·Pingping LiangXiaochen Dong
Dec 10, 2016·ACS Nano·Lu ZhangChunfu Zhang
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