PMID: 6769536May 19, 1980

Operant control of precentral neurons: control of modal interspike intervals

Brain Research
A R WylerC A Robbins


The objects of these experiments were: (a) to determine modal interspike intervals (ISIs) of precentral cells involved in repetitious, gross motor movements; (b) to compare those modal ISIs to the modal ISIs of similar neurons under operant control; and (c) to determine if monkeys could change the modal ISIs of operantly controlled precentral neurons. Data were obtained from 4 monkeys conditioned to produce tonic firing of precentral neurons and one monkey trained to produce repetitious movements of the neck and contralateral limbs. Results are: (a) the modal ISIs from operantly controlled precentral units do not differ significantly from precentral neurons involved in repetitive gross motor movements; and (b) while under operant control, the monkeys cannot modify significantly the modal ISI of the majority of precentral neurons.


Oct 29, 1976·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R N Lemon, R Porter
Oct 29, 1976·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R N LemonR Porter
Sep 1, 1978·Experimental Neurology·E M SchmidtM J Bak
Nov 24, 1978·Brain Research·A R Wyler, K J Burchiel
Sep 14, 1979·Brain Research·A R Wyler, C A Robbins
Mar 1, 1977·Experimental Neurology·E M SchmidtJ S Thomas
Feb 28, 1969·Science·E E Fetz

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