PMID: 111771Jul 27, 1979Paper

Operant control of precentral neurons in monkeys: evidence against open loop control

Brain Research
A R WylerC A Robbins

Abstract

Four normal monkeys were operantly conditioned to change the firing pattern of 111 precentral neurons from phasic to tonic using an operant paradigm which quantifies the control of single neurons. Two monkeys then had their contralateral pyramidal tract (PT) sectioned and one monkey had C5-7 ventral rhizotomies. Postlesion data were: (1) contralateral C1-2PT lesions did not encumber the monkeys' control of precentral PTNs: (2) contralateral C5-7 ventral rhizotomies completely abolished accurate control of precentral neurons which received proprioceptive feedback from flaccid arm regions. These results indicate that precentral neurons are operantly controlled through proprioceptive feedback from peripheral mechanoreceptors. The output of the mechanoreceptors is probably dependent upon discrete joint angles and/or muscle tension which is maintained through non-PT pathways. These data do not support the concept that precentral neurons are operantly controlled directly from a central; 'open loop', pathway.

References

Oct 29, 1976·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R N Lemon, R Porter
Oct 29, 1976·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R N LemonR Porter
Nov 24, 1978·Brain Research·A R Wyler, K J Burchiel
Mar 1, 1977·Experimental Neurology·E M SchmidtJ S Thomas
Feb 28, 1969·Science·E E Fetz

Citations

Sep 14, 1979·Brain Research·A R Wyler, C A Robbins
May 18, 1981·Brain Research·A R Wyler, K J Burchiel
Jun 6, 2002·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jonathan R WolpawTheresa M Vaughan
May 23, 2006·Neurosurgical Focus·R A Bakay
Jan 14, 1982·Brain Research·T D SteegeA R Wyler
Sep 1, 2015·Experimental Brain Research·E J Tehovnik, Lewis L Chen
Aug 18, 1980·Brain Research·A R WylerC A Robbins
Oct 15, 2013·Neuroscience·E J TehovnikW M Slocum

Related Concepts

Anthropoidea
Upper Arm
Operant Conditioning
Hemispheric Specialization
Potentials, Event-Related
Structure of Broca's Area
Joints
Leg
Macaca mulatta
Inotropism

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