Operating characteristics of a qualitative troponin assay for the diagnosis of acute coronary syndrome

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
Davood FarsiMohammad Amin Zare

Abstract

The troponin I serum level is widely used in acute coronary syndrome patients for their classification. The qualitative assay is faster and more available than the quantitative assay. The objective was to determine the operating characteristics of a qualitative troponin I assay compared with a quantitative method. This is a prospective observational study and patients suspected to have acute coronary syndrome were enrolled. A rapid troponin I test and a quantitative assay were carried out for each patient on arrival and 6 h after admission. A total of 262 patients were enrolled. The degree of agreement between the second rapid qualitative and quantitative troponin I was excellent (κ=0.946; 95% confidence interval, 0.903-0.989). The sensitivity, specificity, negative predictive value, and positive predictive value of the rapid qualitative troponin I test were 92.6, 100, 96.8, and 100%, respectively. In conclusion, this study reveals an excellent agreement between quantitative and qualitative bedside assays 6 h after admission in a sample of Iranian patients in the emergency department.

Citations

Sep 5, 2013·International Journal of Cardiology·Madeleine H E Bruins SlotFrans H Rutten
Feb 1, 2017·Annals of Clinical Biochemistry·Valentina PecoraroTommaso Trenti

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