Abstract
Cancers of the paranasal sinuses and nasal cavity are the most common malignant tumors of the anterior and anterolateral skull base. The treatment of these tumors affecting the skull base is complex due to the significant anatomical features. We examined 25 patients, 17 males and 8 females with mean age 61 +/- 2 years. En bloc resections using anterior skull base resection, orbital resection, middle fossa resection, and combined procedures of these three resections were performed. Using a combination of adjuvant radiation and chemotherapy, we have achieved a 2-year disease-free survival rate of 90% in these cases. However, potential complications include cerebrospinal fluid leakage, meningitis, abscess formation, pneumocephalus, frontal brain contusion, trismus, and dysphagia as a functional complication. We believe that the optimal management of such malignant tumors involves a multimodal and multidisciplinary team approach. Here we present our recent institutional experience and treatment policy employed during the past 3 years.
References
Sep 1, 1992·Archives of Otolaryngology--head & Neck Surgery·W J RichtsmeierB S Carson
Apr 1, 1992·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J P ShahE W Strong
Mar 1, 1991·The Laryngoscope·R Van Tuyl, G S Gussack
Dec 1, 1990·Journal of Neurosurgery·O Al-Mefty
Oct 1, 1987·American Journal of Surgery·J P ShahE W Strong
Nov 1, 1980·American Journal of Surgery·J J TerzW Lawrence
Mar 1, 1995·Head & Neck·J R WanamakerP Lavertu
May 1, 1995·Seminars in Surgical Oncology·B W O'Malley, I P Janecka
Nov 1, 1994·Head & Neck·P A LevineR W Cantrell
Jul 1, 1994·Head & Neck·D H KrausE W Strong
Mar 1, 1994·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S Prasad, I P Janecka
May 1, 1994·The Laryngoscope·I P JaneckaH Curtin
Jan 21, 1993·The New England Journal of Medicine·E E VokesW K Hong
May 1, 1997·Journal of Neurosurgery·M H BrismanP Catalano
Apr 4, 1998·Neurosurgery·K NibuA Yamada
Oct 16, 1999·The Laryngoscope·P A LevineR W Cantrell
Nov 24, 1999·Head & Neck·K SaitoJ Yoshida
May 22, 2004·Cancer Control : Journal of the Moffitt Cancer Center·Frank D VrionisTapan A Padhya
Jan 1, 1996·Skull Base Surgery·D G DeschlerM J Kaplan
Citations
Mar 20, 2014·Semergen·M Ruiz-FelipeD Sáenz-Abad
Feb 14, 2013·Acta neurochirurgica·Hiroyuki JimboYukio Ikeda
Oct 1, 2015·International Journal of Oral and Maxillofacial Surgery·G MacíaJ Acero
Apr 17, 2012·Clinical Neurology and Neurosurgery·Rakesh RedhuSwetha H
Mar 28, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Yue-Fei DengYu-Qing Lan
Dec 4, 2015·Current Problems in Diagnostic Radiology·Ashish ChawlaRaymond Chung
Aug 23, 2011·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Kyubo KimJoo-Heon Yoon
Feb 7, 2018·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Yi-Chan LeeKai-Ping Chang
Sep 2, 2017·The Journal of Craniofacial Surgery·Zhong WangJun-Qing Wang
May 12, 2021·Head & Neck·Michael YongEvan Walgama
Nov 20, 2020·The Journal of Craniofacial Surgery·Jianqing HeQingyun Zhang