PMID: 18705423Aug 19, 2008Paper

Ophthalmic manifestations of multiple myeloma

West African Journal of Medicine
A E Omoti, C E Omoti

Abstract

The ophthalmic manifestations of multiple myeloma can be seen in practically every ocular structure. Ocular findings may be the first manifestations of the disease. It may also occur as one of the extramedullary manifestations of the disease or as the first sign of insufficient chemotherapy. Multiple myeloma may cause ocular pathology by direct infiltration or as extramedullary plasmacytomas resulting in displacement or compression of tissues, by causing hyperviscosity syndrome, and by immunoglobulin light chain deposition in ocular tissues. To outline the ophthalmic manifestations of multiple myeloma. Information about multiple myeloma and ophthalmic manifestations was obtained from original journal articles, review articles, case reports and standard postgraduate textbooks. Ophthalmic manifestations include proptosis, diplopia, lid ecchymosis, xanthomatosis, conjunctival and corneal crystalline and non-crystalline deposits, scleritis, episcleritis, secondary glaucoma, ciliary body cysts, ciliochoroidal effusion, uveal plasmacytoma, hyperviscosity retinopathy, retinal vasculitis, detachment of sensory retina and retinal pigment epithelium, and neuro-ophthalmic manifestations. In multiple myeloma, it is necessary to take a clos...Continue Reading

Citations

Dec 29, 2013·Archivos de la Sociedad Española de Oftalmología·S Khaouly, D Vilaplana
Nov 30, 2012·Health Policy and Planning·Gail Tomblin MurphyAmanda Cook
Jun 19, 2009·Current Opinion in Oncology·Oluyemisi AkinwandeClement Adebamowo
Sep 10, 2010·Current Opinion in Hematology·Bernard NatukundaHenk Schonewille
Jun 22, 2011·Obstetrical & Gynecological Survey·Joshua F Nitsche, Thomas Howell
Mar 7, 2013·Pediatric Emergency Care·Muhammad WaseemJaney Peterson

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