Feb 28, 2001

Ophthalmoscopic findings in 3 patients with panarteritis nodosa and review of the literature

Klinische Monatsblätter für Augenheilkunde
D SchmidtP Vaith

Abstract

Ocular involvement in panarteritis nodosa (PAN) has been reported to occur in 10 to 20% of patients. In 3 patients with acute visual disturbance we point out unusual findings. Case 1. A 40-year-old man initially presented with papilledema together with partial optic atrophy in both eyes, later polyneuropathy, gangrene of the toes and myalgic pains developed. Caliber changes in the small arteries in the liver were seen angiographically and recognized as signs of PAN. Under treatment with cyclophosphamide und prednisone no relapse occurred during a follow-up of 2 years. Case 2. In a 67-year-old man who suffered from arterial hypertension and coronary heart disease, central retinal artery occlusion occurred, at first in the left and then later in the right eye. The clinically suspected diagnosis of PAN (arterial hypertension, myalgia, polyneuropathy) was confirmed by a muscle biopsy. During a follow-up of 4 years--including treatment with prednisone and cyclophosphamide--no relapse occurred. Case 3. A 16-year-old adolescent with throbbing headaches and a thickened right temporal artery reported visual disturbances. These were due to an inflammation of choroidal vessels of the right eye appearing as an initial sign of PAN. Histolog...Continue Reading

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Mentioned in this Paper

Polyneuropathy
Choroid
Pulmonary Arterial Hypertension
Arterial System
Right Temporal Artery
Cyclophosphamide
Benign Neoplasm of Choroid
Histology Procedure
Entire Retina
Vision

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