Opinions on registering trial details: a survey of academic researchers.

BMC Health Services Research
Martin Scherer, Sven Trelle

Abstract

The World Health Organization (WHO) has established a set of items related to study design and administrative information that should build the minimum set of data in a study register. A more comprehensive data set for registration is currently developed by the Ottawa Group. Since nothing is known about the attitudes of academic researchers towards prospective study registration, we surveyed academic researchers about their opinion regarding the registration of study details proposed by the WHO and the Ottawa Group. This was a web-based survey of academic researchers currently running an investigator-initiated clinical study which is registered with clinicaltrials.gov. In July 2006 we contacted 1299 principal investigators of clinical studies by e-mail explaining the purpose of the survey and a link to access a 52-item questionnaire based on the proposed minimum data set by the Ottawa Group. Two reminder e-mails were sent each two weeks apart. Association between willingness to disclose study details and study phase was assessed using the chi-squared test for trend. To explore the potential influence of non-response bias we used logistic regression to assess associations between factors associated with non-response and the will...Continue Reading

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Citations

Mar 9, 2011·PloS One·Roderik F Viergever, Davina Ghersi
Jan 16, 2014·PloS One·Roderik F ViergeverDavina Ghersi
Sep 18, 2012·Medicina clínica·Clara Pérez-MañáMagí Farré
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Sep 10, 2011·Journal of Evidence-based Medicine·Udaya K Ranawaka, Colvin Goonaratna
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Oct 25, 2017·PloS One·Harriet A CarrollJames A Betts
Apr 25, 2020·Current Medical Research and Opinion·Hao JinJunwei Liu
Nov 18, 2018·Journal of Evidence-based Medicine·Udaya K RanawakaColvin Goonaratna

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