Opioid-Free Anesthesia for Lung Cancer Resection: A Case-Control Study.

Journal of Cardiothoracic and Vascular Anesthesia
Gary DevineAndrew Roscoe

Abstract

To assess the feasibility and effectiveness of an opioid-free anesthesia (OFA) technique in lung cancer resection surgery versus standard opioid-based techniques. Retrospective, propensity-matched, case-control study. A single, specialty cardiothoracic center between January 2018 and July 2019. Adult patients undergoing lung cancer resection surgery. A cohort of 83 patients undergoing an OFA technique (OFA group) for lung cancer resection surgery was matched with 83 patients who underwent similar surgery with a standard anesthesia technique (STD group). Outcome measures compared between the 2 groups included postoperative pain scores at 0, 1, and 24 hours; 24-hour postoperative morphine patient-controlled analgesia consumption; recovery room and hospital lengths of stay; and 30-day all-cause mortality. No difference was found in median pain scores (interquartile range [IQR]) at 0 hours: STD 0 (0-1), OFA 0 (0-1); p = 0.48. Median pain scores (IQR) at 1 hour were statistically significantly greater in the STD group compared with the OFA group: STD 1 (0-1), OFA 0 (0-1); p = 0.03. There was no difference in median pain scores (IQR) at 24 hours: STD 0 (0-1), OFA 0 (0-1); p = 0.49. Mean postoperative 24-hour patient-controlled analge...Continue Reading

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Citations

Aug 3, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Deepak K Tempe, Chhavi Sawhney
Jun 1, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Michael L BoisenTheresa A Gelzinis

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