Opioid prescribing practices in patients undergoing surgery for oral cavity cancer

The Laryngoscope
John PangCharles S Coffey

Abstract

Opioids have been overprescribed after general and orthopedic surgeries, but prescribing patterns have not been reported for head and neck surgery. The objectives of this retrospective review are to describe postoperative opioid prescriptions after oral cancer surgery and determine which patients receive higher amounts. A single institution retrospective review was performed for 81 adults with oral cavity tumors undergoing surgery. Opioid prescriptions upon discharge were reported in daily oral morphine equivalents (OME). High opioids were defined as > 90 mg daily and > 200 mg total, commensurate with U.S. Center for Disease Control and Prevention and state guidelines. Multivariable logistic regression was performed to investigate factors associated with high opioids. The median number of doses dispensed was 30 (interquartile range [IQR] 30-45; range 3-120). The median daily dose was 30 mg (IQR 20-45 mg; range 15-240 mg). Five patients (6%) received higher than the recommended daily dose. The median total dispensed amount was 225 mg (IQR 150-250 mg; range 15-1200 mg). Fifty-one (63%) received greater than the recommended total dose. On multivariable logistic regression, advanced tumor stage (odds ratio [OR] 11.5; 95% confidence...Continue Reading

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Citations

Jun 13, 2019·The Laryngoscope·Jason E ThuenerChad Zender
Jun 22, 2019·The Laryngoscope·Sophia DangDavid Cognetti
Oct 15, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Juan P CataPascal Owusu-Agyemang
Dec 29, 2020·Head & Neck·Nicole StarrRony K Aouad

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