Opioid Use After ICU Admission Among Elderly Chronic Opioid Users in Ontario: A Population-Based Cohort Study

Critical Care Medicine
Han Ting WangHannah Wunsch

Abstract

Critical illness is often associated with painful procedures and prolonged opioid infusions, raising the concern that chronic opioid users may be exposed to escalating doses that are continued after hospital discharge. We sought to assess patterns of opioid use after intensive care among elderly patients identified as chronic opioid users prior to hospitalization. Population-based cohort study. All adult ICUs in the province of Ontario, Canada. Elderly patients (> 65 yr) admitted to ICUs between April 2002 and March 2015 who also survived to day 180 after hospital discharge, identified as chronic opioid users prior to hospitalization. Chronic opioid use in the year before hospital admission, as well as a filled opioid prescription with a duration covering the day of hospital admission. The primary outcome was the proportion of patients who filled an opioid prescription with a duration covering day 180 after hospital discharge; secondary outcome was the difference in morphine equivalent daily dosage at day 180 after discharge compared with the amount prescribed prior to hospital admission. Of 496,985 elderly admissions to ICUs, 19,584 (3.9%) were chronic opioid users before hospitalization who also survived to day 180 after hosp...Continue Reading

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Citations

Oct 9, 2020·The Journal of Pain : Official Journal of the American Pain Society·Yun ShenAmie J Goodin
Feb 26, 2021·British Journal of Clinical Pharmacology·Juliana de Oliveira CostaSallie-Anne Pearson

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