Opioids for the treatment of chronic non-cancer pain in older people.

Drugs & Aging
Walter GianniF Lattanzio

Abstract

Chronic pain occurs in 45-85% of the geriatric population and the need to treat chronic pain is growing substantially. Unfortunately, treatment for chronic pain is not always correctly targeted, which leads to a reduced quality of life, with decreased socialization, depression, sleep disturbances, cognitive impairment, disability and malnutrition. Considering these consequences, healthcare professionals should aim at improving the diagnosis and treatment of chronic pain in older persons. One of the most important limitations in achieving successful pain management is that older people are not aware that pain management options exist or medications for pain, such as opioids, have associated benefits and adverse effects. Importantly, opioids do not induce any organ failure and if adequately used at the right dosage may only present some predictable and preventable adverse effects. Treating and controlling chronic pain is essential in elderly patients in order to maintain a good quality of life and an active role in both the family and society. To date there are only a few randomized clinical trials testing opioid therapy in elderly patients, and the aim of the present review is to highlight the efficacy and tolerability of opioid...Continue Reading

References

Nov 1, 1976·Anaesthesia·S I RevillM I Hogg
Jan 1, 1991·Therapeutic Drug Monitoring·P A Glare, T D Walsh
Aug 3, 1993·Biochemical Pharmacology·P K PetersonC C Chao
Oct 1, 1998·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D L Schmucker
Aug 24, 1999·International Journal of Immunopharmacology·R JacobsR E Schmidt
Dec 10, 1999·Anesthesia and Analgesia·P S MylesM Reeves
Jul 27, 2000·Annals of the New York Academy of Sciences·C FranceschiG De Benedictis
Jul 19, 2001·Clinics in Geriatric Medicine·S J Gibson, R D Helme
Aug 31, 2001·The American Journal of Chinese Medicine·M S LeeH T Chung
Dec 26, 2001·Archives of Internal Medicine·F LandiR Bernabei
Aug 15, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J L C M DorneA G Renwick
Aug 23, 2002·British Journal of Community Nursing·David T Cowan
Jun 7, 2003·The Clinical Journal of Pain·Mary ErsekBeth Miller Kraybill
Jan 13, 2004·Drugs & Aging·Thorsten Nikolaus, Andrej Zeyfang
Oct 19, 2004·Experimental Gerontology·Anita H J van den BiggelaarRudi G J Westendorp
Mar 2, 2005·European Journal of Pain : EJP·Hans G Kress, Birgit Kraft
Mar 23, 2005·Journal of Pain and Symptom Management·Francesco LandiUNKNOWN SILVERNET-HC Study Group
Apr 13, 2005·Archives of Internal Medicine·Andrea CorsonelloUNKNOWN Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA) Investigators
May 11, 2005·Journal of Manipulative and Physiological Therapeutics·Mitchell HaasAlisa Fairweather
May 25, 2005·Clinics in Geriatric Medicine·Robert L BarkinDiana S Barkin
Jun 4, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Sophie PautexGabriel Gold
Jul 30, 2005·The International Journal of Neuroscience·Kyung Hee YangMyeong Soo Lee
Aug 9, 2005·Current Medical Research and Opinion·Norbert GriessingerRudolf Likar
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Sep 27, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Andrea CorsonelloUNKNOWN Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA)
Apr 19, 2006·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Kazunori ItohHiroshi Kitakoji
Jun 23, 2006·Journal of Internal Medicine·P VestergaardL Mosekilde
Oct 14, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·N AttalUNKNOWN EFNS Task Force
Oct 20, 2006·Journal of Clinical Pharmacology·Mary Beth O'ConnellJune LaValleur
Jan 25, 2007·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rollin M GallagherArnold Gammaitoni
Aug 22, 2007·Complementary Therapies in Medicine·Kazunori ItohHiroshi Kitakoji
Aug 28, 2007·The American Journal of Geriatric Pharmacotherapy·Sally K RiglerLynne Kallenbach
Oct 19, 2007·Southern Medical Journal·Bruce Nicholson, Steven D Passik
Jun 24, 2008·European Journal of Pain : EJP·Hans G Kress
Jun 25, 2008·The Clinical Journal of Pain·Rudolf LikarGerda Ziervogel

❮ Previous
Next ❯

Citations

Jan 5, 2011·Archives of General Psychiatry·Igor ElmanDavid Borsook
Jul 5, 2012·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M RoizenblattS Roizenblatt
Feb 27, 2013·Clinical Interventions in Aging·Beatriz Gras-Miralles, Filippo Cremonini
Jul 7, 2012·Drugs & Aging·Annette L van OjikEric N van Roon
Aug 13, 2013·Postgraduate Medicine·R Norman HardenCharles E Argoff
Aug 4, 2012·Current Medical Research and Opinion·Chris M KozmaGary J Vorsanger
Jul 12, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Maria A Levi-MinziMance E Buttram
Dec 15, 2015·Pharmacoepidemiology and Drug Safety·Nancy A West, Richard C Dart
Jul 6, 2016·Frontiers in Aging Neuroscience·Milica ProstranNataša Cerovac
Aug 1, 2012·Therapeutic Advances in Drug Safety·Sujo AnathhanamJeremy Robson
Dec 18, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Christine MiaskowskiChristine Ritchie
Sep 25, 2020·Primary Health Care Research & Development·Rasa MikelytePatricia M Wilson
Nov 5, 2019·Journal of Pain and Symptom Management·Sophie PaskJason W Boland
Jul 15, 2021·Journal of General Internal Medicine·Monika SalkarYi Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Pain and Symptom Management
Walter GianniStefano Maria Zuccaro
Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Patricia BruckenthalLori Reisner
European Journal of Pain : EJP
Per SjøgrenMorten Grønbaek
© 2021 Meta ULC. All rights reserved