Opportunities for cost-effective prevention of late-life depression: an epidemiological approach

Archives of General Psychiatry
Filip SmitAartjan Beekman

Abstract

Clinically relevant late-life depression has a prevalence of 16% and is associated with substantial societal costs through its disease burden and unfavorable prognosis. From the public health perspective, depression prevention may be an attractive, if not imperative, means to generate health gains and reduce future costs. To target high-risk groups for depression prevention such that maximum health gains are generated against the lowest cost. Population-based cohort study over 3 years. General population in the Netherlands. Twenty-two hundred community residents aged 55 to 85 years. Of these, 1925 were not depressed at baseline. The onset of clinically relevant depression was measured with the Center for Epidemiological Studies Depression Scale. For each of the risk factors (and their combinations), we calculated indices of potential health gain and the effort (costs) required to generate those health gains. One in every 5 cases of clinically relevant late-life depression is a new case. Consequently, depression prevention has to play a key role in reducing the influx of new cases. This is best done by directing prevention efforts toward elderly people who have depressive symptoms, experience functional impairment, and have a sm...Continue Reading

Citations

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