Opposing actions of BMP3 and TGF beta 1 in human bone marrow stromal cell growth and differentiation

Biochemical and Biophysical Research Communications
C FaucheuxJ Amédée

Abstract

BMP3 and TGF beta 1 were found to induce opposite effects on human bone marrow stromal cells both in cell proliferation and cell differentiation and on calcium deposition onto the extracellular matrix. Moreover, BMP3 may exert, in part, the inhibitory effect of TGF beta 1 through decreasing the affinity of TGF-beta for its receptors which are now identified in these human bone cells.

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Citations

Feb 8, 2011·PloS One·Bettina KellerBrendan Lee
Sep 21, 2000·Journal of Cellular Biochemistry·F VillarsJ Amédée
Apr 30, 2004·Oncogene·Zunyan DaiChristoph Plass
Mar 5, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Kurt D Hankenson, Paul Bornstein
May 26, 2005·The Journal of Craniofacial Surgery·Clarice S LawKang Ting
Oct 26, 2005·Journal of Cellular Physiology·Megan A ForemanStephen J Publicover
Mar 7, 2002·American Journal of Physiology. Cell Physiology·F VillarsJ Amédée
Jul 15, 2016·Cold Spring Harbor Perspectives in Biology·Chenbei Chang
Aug 20, 2003·The Journal of Bone and Joint Surgery. American Volume·David L DiefenderferPhoebe S Leboy
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Aug 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Bo HanMarcel E Nimni
Jan 20, 2004·Seminars in Nephrology·Keith A HruskaKameswaran Surendran
Aug 2, 2005·Developmental Biology·Laura W GamerVicki Rosen

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