Optic atrophy in familial dysautonomia

American Journal of Ophthalmology
J F RizzoS D Liebman

Abstract

We examined three patients with classic findings of familial dysautonomia (Riley-Day syndrome) whose visual impairment was associated with optic atrophy. The presence of an optic atrophy in familial dysautonomia is indicative of central nervous system involvement, at least in these cases. Each of these patients was first noted to have visual impairment after the first decade. The late onset of optic atrophy may partly explain its apparent rarity. Since the life span of patients with familial dysautonomia is increasing, optic atrophy may be more commonly recognized in the future.

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Citations

Mar 1, 1991·The Journal of Pediatrics·F B AxelrodC Hazzi
Feb 4, 2014·Journal of Neurology·Carlos E Mendoza-SantiestebanHoracio Kaufmann
Oct 18, 2014·Expert Opinion on Pharmacotherapy·Jose-Alberto PalmaHoracio Kaufmann
Aug 26, 2016·Genetics and Molecular Biology·Paula Dietrich, Ioannis Dragatsis
Oct 12, 2010·Eye & Contact Lens·Langis Michaud, Karen Carrasquillo
Nov 10, 2004·Eye·N J Newman, V Biousse
Sep 16, 2011·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Carlos E Mendoza-SantiestebanHoracio Kaufmann
Apr 3, 2013·Expert Review of Neurotherapeutics·Teresa Neuhann, Bernd Rautenstrauss

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