Optic chiasm astrocytomas of childhood. 2. Surgical management

Pediatric Neurosurgery
M D Medlock, R M Scott

Abstract

We presented our experience from 1975 to 1994 with emphasis on the long term follow-up of children with optic chiasm astrocytomas in part I. In part II we describe the surgical management of 20 patients with the diagnosis of an astrocytoma of the optic chiasm confirmed by biopsy. These patients underwent surgery by the senior author between 1988 and 1994. The patients and the tumors in this series are comparable in age, sex, and presentation and imaging characteristics to other series. Surgery was undertaken with the intent to reduce tumor volume and mass effect and in certain cases to confirm the diagnosis. The patients' mean age at the time of surgery was 81 (range 18-216) months. The surgical approaches used were pterional in 11 patients, transorbital/subfrontal in 8, and subfrontal in 1 patient. Greater than 50% of the tumor was resected in 8 patients, less than 50% was resected in 9, and biopsy only was achieved in 3 patients. Larger tumors were more likely to have magnetic resonance imaging documented debulking of tumor. Permanent morbidity included mild visual loss, diabetes insipidus, mild hemiparesis, and panhypopituitarism in 1 patient each. There was no surgical mortality. The likelihood of resecting greater than 50%...Continue Reading

Citations

Jan 17, 2009·Pediatric Blood & Cancer·Valérie de HaasChantal Kalifa
Jan 18, 2006·Pediatric Blood & Cancer·Christopher D Jahraus, Nancy J Tarbell
Jul 22, 2009·Pediatric Blood & Cancer·Gary NicolinEric Bouffet
Nov 17, 2007·Neurosurgical Focus·Mandy J BinningMarion L Walker
Oct 22, 2013·Journal of Neurosurgery. Pediatrics·John GooddenConor Mallucci
Aug 19, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Kristian AquilinaFrederick A Boop
Mar 6, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·F W NeervoortW P Vandertop
Nov 5, 2014·Journal of Neuro-oncology·Andrea Maria CappellanoEric Bouffet
Nov 25, 2020·Neuro-Chirurgie·Irene StellaOlivier Klein

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