Optic disk appearance in advanced age-related macular degeneration

American Journal of Ophthalmology
Simon K LawJ Caprioli

Abstract

To describe and quantify the appearance of the optic disk in patients with advanced age-related macular degeneration (ARMD). Retrospective comparative study. A total of 316 charts were reviewed. From these, 45 subjects with advanced ARMD (defined as geographic atrophy or disciform scar) in at least one eye were enrolled. Patients with glaucoma or glaucoma visual field defects were excluded. The probability of glaucomatous optic nerve damage was scored by evaluation of stereoscopic optic disk photographs in a masked fashion, according to a predefined evaluation scale and measured with confocal ophthalmoscopy (Heidelberg Retinal Tomograph; HRT). The area of macular involvement was measured in units of disk area. The optic disk evaluation scores and HRT measurements of a group of eyes with a large area of ARMD were compared with their fellow eyes with smaller areas of ARMD. The correlations between the area of macular involvement with the optic disk evaluation scores and HRT measurements were analyzed. The optic disk evaluation scores and the HRT measurements between study groups. Eyes with larger areas of ARMD had optic disks that were more likely to be classified as glaucomatous by clinical evaluation (3.45 +/- 0.23 vs 3.05 +/- ...Continue Reading

References

May 1, 1976·The British Journal of Ophthalmology·S H Sarks
Jan 1, 1990·Archives of Ophthalmology·H A QuigleyS M Drance
Mar 1, 1996·Archives of Ophthalmology·E B DreyerS A Lipton
May 1, 1996·American Journal of Ophthalmology·L BrigattiJ Caprioli
Mar 11, 1998·Journal of Glaucoma·E B Dreyer
Jun 17, 1998·Experimental Eye Research·L Carter-DawsonA Chuang
Oct 27, 1999·The British Journal of Ophthalmology·J B Jonas, S S Hayreh
Apr 28, 2001·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·G C Chiou
Jan 30, 2002·The British Journal of Ophthalmology·Thomas A CiullaHanna J Garzozi
Nov 13, 2002·Archives of Ophthalmology·Joshua L DunaiefAnn H Milam
Feb 14, 2003·Archives of Ophthalmology·Robert A HonkanenYoung H Kwon
Nov 20, 2015·Ophthalmology·Bruce E PrumRuth D Williams

❮ Previous
Next ❯

Citations

Nov 3, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kentaro YudaYasuo Yanagi
Mar 1, 2012·Computer Methods in Biomechanics and Biomedical Engineering·Ayşegül Güven
Jul 6, 2004·American Journal of Ophthalmology·Wallace L M Alward
Feb 24, 2006·American Journal of Ophthalmology·Ellen R HallRonald Klein
Feb 9, 2018·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Hyung-Bin LimJung-Yeul Kim
Oct 2, 2013·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Sadananda B Naik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.