Optic disk appearance in pseudoexfoliation syndrome

American Journal of Ophthalmology
Jost B Jonas, K I Papastathopoulos

Abstract

To evaluate the optic disk appearance in eyes with pseudoexfoliation syndrome. Clinical data and color stereo optic disk photographs of 99 patients with pseudoexfoliative glaucoma and 42 nonglaucomatous subjects with pseudoexfoliation syndrome were compared with those of 658 patients with primary open-angle glaucoma and of 364 normal subjects. Mean optic disk area was significantly (P = .009) smaller in the pseudoexfoliative glaucomatous eyes (mean +/-SD, 2.52 +/- 0.49 mm2) than in the primary open-angle glaucoma eyes (2.71 +/- 0.63 mm2). Correspondingly, mean optic disk area was significantly (P = .04) smaller in the pseudoexfoliative nonglaucomatous eyes (2.48 +/- 0.52 mm2) compared with the normal eyes without pseudoexfoliation (2.67 +/- 0.67 mm2). Comparing the pseudoexfoliative subgroups with the nonpseudoexfoliative subgroups separately in the glaucomatous and the nonglaucomatous groups, no significant differences were found for neuroretinal rim area, size of alpha and beta zones of the parapapillary atrophy, and diameters of the retinal arterioles and venules at the disk border. In the glaucomatous group, the maximal intraocular pressure measurements were significantly (P < .001) higher in the pseudoexfoliative subgroup ...Continue Reading

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