Optic nerve hypoplasia associated with pupillary light-near dissociation, spastic paraparesis and other non-ocular anomalies

Italian Journal of Neurological Sciences
D DoroF Moro

Abstract

We report a case of bilateral optic nerve hypoplasia in a patient with pupillary light-near dissociation, spastic paraparesis with deep hyperreflexia, mild distal hypotrophy especially of lower limbs, bilateral pes cavus and signs of motor peripheral neuropathy. Other associated signs were rhinolalia, hypotrophy and fasciculations of the tongue and cardiomyopathy. We differentiate the condition from a number of hereditary ataxias and paraplegias. The clinical features of Strümpell-Lorrain spastic paraplegia and amyotrophic lateral sclerosis seem to resemble most closely that of our patient.

References

Sep 1, 1979·American Journal of Ophthalmology·V Boniuk, P K Ho
Mar 1, 1979·Brain : a Journal of Neurology·P J SpiraW A Evans
May 1, 1979·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·A Barbeau
Jun 1, 1977·Neurology·G W Hogan, M L Bauman
Mar 1, 1979·Neurology·D S HoroupianH D Peterson
Oct 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·G L Holmes, B A Shaywitz
Oct 1, 1978·American Journal of Ophthalmology·A BjörkU Laurell
Jun 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·J G McLeodC Reye
Apr 25, 1970·Lancet·W F HoytJ S Glaser
Sep 1, 1972·Archives of Ophthalmology·H B Gardner, A R Irvine
Jun 1, 1972·American Journal of Ophthalmology·R L Seeley, J L Smith
Nov 1, 1970·Archives of Ophthalmology·D S Walton, R M Robb
Dec 1, 1970·American Journal of Ophthalmology·W C Edwards, W E Layden
May 1, 1967·Archives of Neurology·H E Cross, V A McKusick
Jun 1, 1984·Developmental Medicine and Child Neurology·D MargalithJ Lapointe
Jan 1, 1980·American Journal of Ophthalmology·W Krause-Brucker, D W Gardner
Aug 1, 1980·Journal of Neurology, Neurosurgery, and Psychiatry·A E Harding, P K Thomas

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