Optic neuritis

Neurologic Clinics
David ClarkEric Eggenberger

Abstract

Optic neuritis usually presents with painful monocular vision loss in younger patients. Spontaneous improvement in vision occurs over weeks, and treatment with high-dose intravenous steroids increases the rate but not extent of visual recovery. Risk of progression to multiple sclerosis (MS) is largely dictated by baseline brain magnetic resonance imaging (MRI). Those with a normal MRI finding at the time of optic neuritis diagnosis have a lower rate of progression to multiple sclerosis than those with T2 hyperintense white matter lesions on MRI. High-dose intravenous steroids should be considered acutely in optic neuritis, and disease-modifying therapy should be considered in patients at high risk of MS as defined by MRI.

References

Mar 1, 1995·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·N G SwartzB Katz
Feb 1, 1995·Neurology·M RodriguezL T Kurland
Oct 9, 2001·American Journal of Ophthalmology·UNKNOWN CHAMPS Study Group
May 24, 2006·Annals of Neurology·Fiona CostelloRandy H Kardon
Nov 1, 2008·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Fiona CostelloRandy H Kardon

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Citations

Feb 24, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Oliver W GramlichFranz H Grus
Jun 9, 2015·La Revue de médecine interne·S AbbaraE Cogan
Aug 30, 2014·Neurologia i neurochirurgia polska·Waldemar BrolaJózef Opara
Sep 15, 2015·Current Opinion in Ophthalmology·Devin D Mackay

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