Optical bio-chemical sensors based on whispering gallery mode resonators

Nanoscale
Ya-Nan ZhangYong Zhao

Abstract

Whispering gallery mode (WGM) resonators have attracted extensive attention and their unique characteristics have led to some remarkable achievements. In particular, when combined with optical sensing technology, the WGM reonator-based sensor offers the advantages of small size, high sensitivity and a real-time dynamic response. At present, this type of sensor is widely applied in the bio-chemical sensing field. In this paper, we briefly review the sensing principle, the structures and the sensing applications of optical bio-chemical sensors based on the WGM resonator, with particular focuses on their sensing properties and their advantages and disadvantages. In addition, the existing problems and future development trends of WGM resonator-based optical bio-chemical sensors are discussed.

References

Jul 25, 2003·Analytical and Bioanalytical Chemistry·Jirí Homola
Aug 29, 2003·Biophysical Journal·Frank VollmerAlbert Libchaber
May 28, 2004·Nature·Gerda EggerPeter A Jones
Jan 5, 2006·Optics Letters·A Ksendzov, Y Lin
Apr 28, 2006·Optics Letters·Ian M WhiteXudong Fan
Oct 30, 2007·Biosensors & Bioelectronics·A RamachandranB E Little
Nov 27, 2007·Biosensors & Bioelectronics·Jonathan D SuterXudong Fan
Nov 28, 2007·Optics Letters·V S IlchenkoL Maleki
Jan 25, 2008·Faraday Discussions·S ArnoldI Teraoka
Feb 15, 2008·Analytical Chemistry·Siyka I ShopovaShiou-jyh Ja
Apr 17, 2008·Optics Letters·Yuze SunXudong Fan
Jun 14, 2008·Biosensors & Bioelectronics·Hongying ZhuXudong Fan
Jul 1, 2008·Nature Methods·Frank Vollmer, Stephen Arnold
Jul 9, 2008·Optics Express·Jonathan D SuterXudong Fan
Jul 9, 2008·Optics Express·Yuze Sun, Xudong Fan
Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·F VollmerD Keng
May 13, 2009·Optics Express·Paul E BarclayOskar Painter
Jul 23, 2007·Optics Express·Hongying ZhuXudong Fan
Dec 10, 2007·Optics Express·Hai-Cang RenAlbert Libchaber
Dec 10, 2007·Optics Express·Ian M WhiteXudong Fan
Jun 30, 2009·The Analyst·Yuze SunXudong Fan
Mar 12, 2010·Lab on a Chip·Allen H J Yang, David Erickson
Apr 7, 2010·Optics Letters·M SumetskyR S Windeler
Mar 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Tao LuKerry Vahala
Jun 3, 2011·Optics Letters·Amy WatkinsSíle Nic Chormaic
Sep 8, 2011·Journal of Biomedical Optics·Jing Wu, Min Gu
Dec 6, 2011·Optics Letters·Rico HenzeOliver Benson
Jan 1, 2010·Sensors·Heather K HuntAndrea M Armani
Jan 4, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Martin Baaske, Frank Vollmer

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Citations

Mar 14, 2019·Nanoscale·Zhang ZhangLimin Tong
Oct 6, 2020·APL Photonics·Maria SolerAndrea M Armani
Dec 28, 2019·Optics Express·Xiaoming MaJiaxiong Fang
Jul 7, 2020·Optics Letters·Haoye QinMing Ding
Apr 1, 2021·Advanced Photonics Research·Yuzhi ShiAi Qun Liu
May 2, 2021·Biosensors & Bioelectronics·Abdullah RedaMohamed A Shenashen
Jun 10, 2021·Nanoscale·Kun GeTianrui Zhai

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Methods Mentioned

BETA
biosensor
biosensors
chip
biosensing
phage display
surface plasmon resonance
imaging techniques
surface plasmon resonances

Software Mentioned

wholly
spot

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