Optical coherence tomography angiography and microvascular changes in diabetic retinopathy: a systematic review

Acta Ophthalmologica
Sunniva Kruse JohannesenJakob Grauslund

Abstract

To use optical coherence tomography angiography (OCTA) to evaluate foveal microvascular changes in diabetes by comparing the area of foveal avascular zone (FAZ) in healthy controls and patients with diabetes with no diabetic retinopathy (NDR) as well as different stages of diabetic retinopathy (DR). A systematic literature search was performed based on the population, intervention, comparison and outcome (PICO) strategy by two independent reviewers. The search was performed in PubMed, Embase and Cochrane Library, including keywords 'diabetes mellitus', 'DR' and 'OCTA'. Of 358 studies initially identified, 215 studies were screened after duplicate removal. Of these, we included 12 (nine cross-sectional and three retrospective) studies in this review. With the data at hand, it was not possible to perform a meta-analysis. The selected studies included patients with NDR (n = 8), non-proliferative diabetic retinopathy (NPDR, n = 8) and proliferative diabetic retinopathy (PDR, n = 6). Several of the studies provided information for more than one diabetic group. In general, there was a trend towards a larger area of FAZ in patients with diabetes. As compared to healthy controls, this was reported in patients with NDR (five of eight st...Continue Reading

References

Sep 1, 1984·Archives of Ophthalmology·G H BresnickK Korth
Oct 3, 2000·Ophthalmic Research·C Delaey, J Van De Voorde
Sep 15, 2007·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Candis M Morello
Feb 5, 2010·Investigative Ophthalmology & Visual Science·Yalin ZhengSimon P Harding
Nov 1, 2011·Investigative Ophthalmology & Visual Science·Johnny TamAustin Roorda
Jan 1, 2014·World Journal of Diabetes·Lihteh WuMarissé Masis
Apr 10, 2014·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Jun Zeng, Baihua Chen
Apr 22, 2015·American Journal of Ophthalmology·Akihiro IshibazawaAkitoshi Yoshida
Sep 5, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Florentina J FreibergStephan Michels
Sep 8, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gong DiDong Fangtian
Oct 3, 2015·Ophthalmic Surgery, Lasers & Imaging Retina·Douglas R MatsunagaAmir H Kashani
Jun 18, 2016·Frontiers in Physiology·Priyia PusparajahKhalid Abdul Kadir
Jul 30, 2016·Investigative Ophthalmology & Visual Science·Mayss Al-SheikhSriniVas R Sadda
Jul 30, 2016·Investigative Ophthalmology & Visual Science·Devanshi BhanushaliAbhijit Sinha Roy
Nov 9, 2016·Clinical Epidemiology·Nis AndersenJens Andresen
Apr 15, 2015·International Journal of Retina and Vitreous·Talisa E de CarloJay S Duker
Jan 24, 2017·Investigative Ophthalmology & Visual Science·Galina DimitrovaKazushiro Okazaki
Jul 25, 2017·The Lancet. Diabetes & Endocrinology· The Lancet Diabetes Endocrinology
Oct 31, 2017·The Lancet. Diabetes & Endocrinology· The Lancet Diabetes Endocrinology

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Citations

Jan 15, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·UNKNOWN Deutsche Ophthalmologische Gesellschaft (DOG)UNKNOWN Berufsverband der Augenärzte Deutschlands e. V. (BVA)
Jan 8, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Peter M MalocaUNKNOWN IOB study group
Aug 21, 2020·Translational Vision Science & Technology·Morgan HeislerMarinko V Sarunic
Sep 4, 2020·Vestnik oftalmologii·D V Petrachkov, M V Budzinskaya
Sep 22, 2020·Therapeutic Advances in Ophthalmology·Ashish MarkanVishali Gupta
Oct 10, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·UNKNOWN German Society of Ophthalmology (DOG)UNKNOWN Professional Association of Ophthalmologists in Germany (BVA)
Nov 4, 2020·Journal of Magnetic Resonance Imaging : JMRI·Huihui WangZhenchang Wang
Apr 15, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kalie L TommerdahlPetter Bjornstad
Jul 9, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Patryk SidorczukDiana Dmuchowska

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