Optical coherence tomography angiography in patients with retinitis pigmentosa who have normal visual acuity

Acta Ophthalmologica
Seiji TakagiYasuo Kurimoto

Abstract

To investigate flow area changes measured using optical coherence tomography angiography (OCTA; RTVue XR Avanti® ) in patients with retinitis pigmentosa (RP) with preserved visual acuity (VA). This was an age- and refraction-matched case-control study. Consecutive patients with a best-corrected visual acuity (BCVA) of ≥20/20 and normal subjects were recruited. Fifty eyes (32 patients) and 22 eyes (12 controls) were included. The flow area and foveal avascular zone (FAZ) were measured in both superficial and deep layers within a 3 × 3 mm central area of the fovea. Association between OCTA parameters and the length of the inner segment ellipsoid (ISe) and external limiting membrane (ELM), the area without abnormal fluorescence in fundus autofluorescence (normal FAF area ratio) and the area of I-2e of the Goldmann perimeter were analysed using mixed-effects regression analysis. Foveal avascular zones were significantly smaller in patients with RP than in controls in superficial (p = 0.004) but not in deep layers (p = 0.25). The flow area in superficial (p = 0.007) and deep layers (p = 0.004) was significantly smaller in patients with RP than in controls. In patients with RP, flow areas in the superficial layers, but not in the dee...Continue Reading

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Citations

Dec 5, 2019·Journal of Clinical Medicine·Sally S OngMandeep S Singh
Sep 11, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Margarita G TodorovaMaria Della Volpe Waizel
Dec 7, 2018·Journal of Alzheimer's Disease : JAD·Larissa LahmeMaged Alnawaiseh
Dec 21, 2018·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·N MihailovicM Alnawaiseh
Oct 11, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Olga ZabekMaria Della Volpe Waizel
May 12, 2021·Acta Ophthalmologica·Maria Della Volpe WaizelMargarita G Todorova
Jan 5, 2022·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sebastian DeutschUlrich Kellner

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Methods Mentioned

BETA
imaging technique
imaging techniques

Software Mentioned

Optovue
OCTA
SPSS
imagej

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