Optical Coherence Tomography Angiography of Shallow Irregular Pigment Epithelial Detachments In Pachychoroid Spectrum Disease

American Journal of Ophthalmology
Kunal K DansinganiK Bailey Freund

Abstract

To determine the proportion of shallow irregular pigment epithelial detachments in eyes with pachychoroid features that harbor neovascular tissue and to study the morphology of this tissue with optical coherence tomography (OCT) angiography. Prospective consecutive cohort study. Patients with pachychoroid spectrum diagnoses and shallow irregular pigment epithelial detachment in at least 1 eye (study eye) were included. Charts and multimodal imaging were reviewed to determine a dye angiography detection rate for type 1 neovascularization in study eyes. All patients then underwent OCT angiography prospectively, followed by masked segmentation and grading. Twenty-two eyes of 16 patients were included. Mean age was 71 (range 57-95) years. Mean subfoveal choroidal thickness was 381 μm (standard deviation: 141 μm). Four out of 22 study eyes (18%) exhibited polypoidal lesions. Dye angiography demonstrated specific features of neovascularization in 5 out of 17 eyes (29%) with suspected nonpolypoidal pachychoroid neovasculopathy. With OCT angiography, type 1 neovascular tissue was visualized in 21 out of 22 study eyes (95%). Our data suggest that, in eyes with pachychoroid features, the finding of a shallow irregular pigment epithelial ...Continue Reading

References

Aug 1, 1994·Archives of Ophthalmology·D R GuyerD Orlock
Aug 26, 1998·Ophthalmology·R S MoorthyL M Jampol
Nov 24, 1999·Archives of Ophthalmology·L A YannuzziD A Orlock
Sep 26, 2003·Investigative Ophthalmology & Visual Science·Ursula Schmidt-ErfurthGottfried O H Naumann
Mar 12, 2004·American Journal of Ophthalmology·Hans E Grossniklaus, W Richard Green
Nov 9, 2004·Survey of Ophthalmology·Vikas KhetanNitin S Shetty
Apr 6, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Keiichi MitaraiYasuo Tano
Aug 16, 2012·Archives of Ophthalmology·Sri Krishna MukkamalaK Bailey Freund
Aug 18, 2012·Survey of Ophthalmology·Pearse A KeaneAdnan Tufail
May 21, 2013·The British Journal of Ophthalmology·Vasilios P PapastefanouMandeep S Sagoo
Jun 6, 2013·Investigative Ophthalmology & Visual Science·Lihong YangWenbin Wei
Jun 12, 2013·Retina·David J WarrowK Bailey Freund
Jun 26, 2013·American Journal of Ophthalmology·Sally L BaxterJohn H Kempen
Nov 10, 2013·Investigative Ophthalmology & Visual Science·Amirhossein HaririSriniVas R Sadda
May 6, 2014·American Journal of Ophthalmology·Claudine E PangK Bailey Freund
Aug 28, 2014·Retina·Claudine E Pang, K Bailey Freund
Jan 1, 2009·Retinal Cases & Brief Reports·Enrico PeirettiRichard F Spaide
Jun 23, 2015·Investigative Ophthalmology & Visual Science·Priscilla Ern Zhi TanDao-Yi Yu
Jul 15, 2015·American Journal of Ophthalmology·Laura KuehleweinDavid Sarraf

❮ Previous
Next ❯

Citations

Oct 21, 2015·Progress in Retinal and Eye Research·Daniela FerraraJay S Duker
Jan 15, 2016·American Journal of Ophthalmology·Kunal K DansinganiDavid Sarraf
Mar 8, 2016·Experimental Eye Research·Maged AlnawaisehNicole Eter
Mar 18, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Eduardo A NovaisJay S Duker
Apr 27, 2016·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Jessica I W Morgan
Aug 11, 2016·Ophthalmology·Kunal K DansinganiK Bailey Freund
Sep 18, 2016·American Journal of Ophthalmology·Anna C S TanLawrence A Yannuzzi
Mar 21, 2018·European Journal of Ophthalmology·Salomon Y CohenSarah Mrejen
Apr 7, 2018·European Journal of Ophthalmology·Marco LupidiCarlo Cagini
Mar 23, 2018·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Chung Yee ChungKenneth K W Li
Jun 27, 2018·Indian Journal of Ophthalmology·Guruprasad AyachitShrinivas Joshi
Jul 12, 2018·Eye·Chui Ming Gemmy CheungK Bailey Freund
Nov 15, 2017·Retina·Nopasak PhasukkijwatanaDavid Sarraf
Nov 6, 2018·Clinical & Experimental Ophthalmology·Jiwon BaekWon Ki Lee
Dec 15, 2018·Investigative Ophthalmology & Visual Science·Nobuhiro TeraoJunji Hamuro
Jan 15, 2019·Ophthalmic Surgery, Lasers & Imaging Retina·Peter H TangRuwan A Silva
Dec 1, 2017·Retina·Elon H C van DijkCamiel J F Boon
Feb 27, 2019·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Han Joo ChoJong Woo Kim
Jan 15, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·Atsuro UchidaJustis P Ehlers
Nov 9, 2016·Retinal Cases & Brief Reports·Gaetano R Barile, Sarah A Harmon
Apr 30, 2020·Ophthalmic Surgery, Lasers & Imaging Retina·K Bailey Freund, Howard F Fine
Jun 22, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jiwon BaekWon Ki Lee
Apr 4, 2017·Journal of Current Ophthalmology·Khalil Ghasemi Falavarjani, David Sarraf
Feb 20, 2019·Indian Journal of Ophthalmology·Sumit Randhir SinghJay K Chhablani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Retina
Claudine E Pang, K Bailey Freund
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Rogério A CostaMichel E Farah
American Journal of Ophthalmology
Akitaka TsujikawaNagahisa Yoshimura
Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
Shabeeba R HannanRichard S B Newsom
© 2021 Meta ULC. All rights reserved