Optical coherence tomography angiography of superficial retinal vessel density and foveal avascular zone in myopic children

PloS One
Joanna GołębiewskaWojciech Hautz

Abstract

To assess the superficial retinal vessel density (SRVD) and foveal avascular zone (FAZ) in myopic children using optical coherence tomography angiography (OCTA). 174 eyes of 89 subjects with myopia and 101 eyes of 54 age-matched, emmetropic volunteers (control group) were enrolled in this study. The mean age of the subjects and controls was 13.9 (SD ± 2.3) and 13.1 (SD ± 2.4), respectively. Myopia was defined as spherical equivalent <- 1.0 diopter. Emmetropic subjects were defined as having spherical equivalent from + 0.5 to - 0.5 diopter. The mean axial length (AL) in myopic patients was 24.58 mm (SD ± 1.22) and 22.88 mm (SD ± 0.65) in the controls. Every patient underwent a complete ophthalmological examination and OCTA, using AngioVue (Optovue). The FAZ area and superficial retinal vessel density, including whole SRVD, fovea SRVD and parafovea SRVD, were analyzed. Foveal thickness (FT) and parafoveal thickness (PFT) were also taken into consideration. Whole SRVD, parafovea SRVD and PFT were significantly higher in controls than in the myopic subjects (p < 0.001, p = 0.007, p < 0.01, respectively). The FAZ area was significantly larger in the myopic group compared to the controls (p = 0.010). Fovea SRVD and FT did not differ ...Continue Reading

References

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Citations

Jun 4, 2020·Scientific Reports·Hanieh MirhajianmoghadamJason Porter
Jan 7, 2020·European Journal of Ophthalmology·Elif Güler KazancıMehmet Erol Can
Mar 25, 2021·Current Eye Research·Pilar Pérez-GarcíaJose María Martinez-de-la-Casa
Jul 19, 2020·American Journal of Ophthalmology·Jesse J JungQuan V Hoang
Apr 12, 2021·Microvascular Research·Zhang XiuyanBi Hongsheng
Jul 29, 2021·Investigative Ophthalmology & Visual Science·Hao WuXiangtian Zhou
Aug 21, 2021·Scientific Reports·Helong PiaoSang Woo Park
Feb 15, 2022·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Pelsin DemirAntonio Filipe Macedo
Feb 19, 2020··Vasudevan LakshminarayananJothi J. Balaji

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Software Mentioned

Matlab script
Stata
AngioVue

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