Optical coherence tomography for the noninvasive evaluation of the cornea

Cornea
K HiranoY Miyake

Abstract

To determine the optical coherence tomographic (OCT) characteristics of normal corneas and to characterize the OCT images of abnormal corneal lesions. Eleven eyes from 10 patients were examined at the Cornea Service of the Nagoya University Hospital: 4 had corneal pathologies, 4 underwent keratoplasty, and 2 were normal controls; 1 enucleated eye was also examined. OCT (OCT 2000 Zeiss-Humphrey) was used to study the normal cornea and various corneal abnormalities. We compared the OCT images to the observations made by slit-lamp biomicroscopy. Fluid spaces were detected as black images. A highly reflective reflex was observed at the interface of different tissues, and intensive backscattering (reflex) was seen when the incident ray hit the laminated layers vertically. Corneal opacities were not clearly imaged when they were diffuse and mild, or when they were arranged axially in a small area, as was the scar of the graft-host junction. It was possible to obtain images from the region of the cornea that was not clearly visible by slit-lamp examination because of a corneal opacity. OCT is a noncontact and noninvasive technique that can be performed safely on diseased corneas. OCT can provide objective documentation of corneal diso...Continue Reading

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Citations

Sep 4, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Edward WylegalaDorota Tarnawska
Mar 19, 2004·Survey of Ophthalmology·Mehran TabanPeter J McDonnell
Dec 4, 2003·Ophthalmology·Peter J McDonnellZhongping Chen
Apr 26, 2002·Cornea·Shu Kachi, Koji Hirano
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Nov 15, 2006·Cornea·Bartłomiej J KaluznyPiotr Targowski
Oct 8, 2013·Cornea·Andrea CruzatKathryn Colby
May 19, 2005·Journal of Cataract and Refractive Surgery·Gary R FishmanRobert Ritch
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Feb 11, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Luigina SorbaraNatalie Hutchings
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Nov 21, 2012·Seminars in Ophthalmology·Rony R Sayegh, Roberto Pineda
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Aug 13, 2021·Translational Vision Science & Technology·Weihao ChenKatia Del Rio-Tsonis

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