Optical diagnosis of lower urinary tract infection: a pilot study in children

Journal of Pediatric Urology
Babak ShadganA M Kajbafzadeh

Abstract

Conventionally, diagnosis of lower urinary tract infection (LUTI) is made on the basis of history, urine microscopy and culture. But there are limitations to this methodology especially in children and special populations where there is difficulty in obtaining a full history and details of clinical symptoms. The aim of this study was to determine if monitoring bladder wall oxygenation as a measure of bladder mucosal inflammation using transcutaneous near-infrared spectroscopy (NIRS) allows detection of the presence or absence of LUTI in children. A convenience sample of children referred to a pediatric urology clinic with an acute LUTI and a control group were studied. Diagnosis was confirmed by history, physical examination, laboratory investigations, and urine culture. Participants had transcutaneous measurement of an absolute measure of tissue oxygen saturation (TSI%) in their bladder wall, and a quadriceps muscle control site, using a spatially resolved (SR) wireless NIRS device. Average measures of bladder wall TSI% (B.TSI%) and quadriceps TSI% (Q.TSI%) and their differences (TSI.diff) were calculated and compared between those with LUTI and controls by performing a two-way repeated analysis of variance. Thirty-four patien...Continue Reading

References

Aug 5, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R M EcholsA D Tice
Jun 5, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Zhina SadeghiAzadeh Elmi
Jul 6, 2010·Anesthesia and Analgesia·Raghavendra GovindaOzan Akça
Aug 20, 2011·Current Infectious Disease Reports·Frederiek D'Hondt, Karel Everaert
Dec 4, 2012·Expert Review of Anti-infective Therapy·Maria Bitsori, Emmanouil Galanakis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.